Prescription medicine

Atropine and pralidoxime Brand names: Duodote; first approved as Atnaa

Atropine and pralidoxime (Duodote) is a prescription medicine with an FDA approval on record since 2002. No generic is listed in FDA's NDC Directory.

No generic listed

Check it at the source: the atropine and pralidoxime FDA label on DailyMed (effective April 4, 2022, Meridian Medical Technologies LLC); the NDA 21175 record on Drugs@FDA; every atropine and pralidoxime label on DailyMed.

Highlights of the record

FDA label of April 4, 2022; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026

Used for

From the label: indications and usage
DuoDote is indicated for the treatment of poisoning by organophosphorus nerve agents as well as organophosphorus insecticides in adults and pediatric patients weighing more than 41 kg (90 pounds).

Forms and strengths

Kit.

On the market

Earliest approval on file: January 17, 2002 Atnaa, Us Army; Drugs@FDA’s file, where older or withdrawn approvals can be missing
Generic approvals: No generic approved
Labelers listed (NDC): 2 of which 0 under generic applications, 2 under brand applications, repackagers included

Supply and safety

Pharmacy cost (NADAC): Not in the survey
Shortage (FDA): No current entry
Recalls by its makers (FDA): No recall recorded

What is atropine and pralidoxime used for?

From the label: indications and usage
DuoDote is indicated for the treatment of poisoning by organophosphorus nerve agents as well as organophosphorus insecticides in adults and pediatric patients weighing more than 41 kg (90 pounds). DuoDote, a combination of atropine, a cholinergic muscarinic antagonist, and pralidoxime chloride, a cholinesterase reactivator, is indicated for the treatment of poisoning by organophosphorus nerve agents as well as organophosphorus insecticides in adults and pediatric patients weighing more than 41 kg (90 pounds).

Source: FDA drug label (DuoDote), NDA021983 (Mmt), as published by Meridian Medical Technologies LLC, effective April 4, 2022 (SPL set 241f42a0-1a33-40e8-8221-201767d999e5), via openFDA; the full label on DailyMed

Is there a generic for atropine and pralidoxime (Duodote)?

No generic atropine and pralidoxime is approved (Drugs@FDA, October 8, 2026).

2002 earliest approval on file

Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)

What does the atropine and pralidoxime label say about other medicines?

The atropine and pralidoxime label names 1 other medicine in its interaction, contraindication or warning sections. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.

Medicine named	Section	What the label says
Succinylcholine	drug interactions	DRUG INTERACTIONS Succinylcholine and Mivacurium: Accelerated reversal of neuromuscular blocking effects may occur; monitor with concomitant administration.

Check atropine and pralidoxime against other medicines

What next?

Check an interaction: what two or more labels say about each other