Prescription medicine
Calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate Brand names: Extraneal
Calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate (Extraneal) is a prescription medicine. No generic is listed in FDA's NDC Directory.
- No generic listed
Check it at the source: the calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate FDA label on DailyMed (effective June 30, 2025); every calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate label on DailyMed.
Highlights of the record
FDA label of June 30, 2025; NDC Directory, Drugs@FDA and Orange Book, October 8, 2026
Used for
From the label: indications and usageEXTRANEAL (icodextrin) is indicated for a single daily exchange for the long (8- to 16- hour) dwell during continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) for the management of kidney failure in patients requiring long-term kidney replacement therapy.
Forms and strengths
- 7.5 g/100ml / 535 mg/100ml / 448 mg/100ml / 25.7 mg/100ml / 5.08 mg/100ml
Injection (solution).
On the market
- Generic approvals
- No generic approved
- Labelers listed (NDC)
- 1 of which 0 under generic applications, 1 under brand applications, repackagers included
Supply and safety
- Pharmacy cost (NADAC)
- Not in the survey
- Shortage (FDA)
- No current entry
- Recalls by its makers (FDA)
- No recall recorded
- FAERS reports
- 30,880 through July 30, 2026
What is calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate used for?
From the label: indications and usageEXTRANEAL (icodextrin) is indicated for a single daily exchange for the long (8- to 16- hour) dwell during continuous ambulatory peritoneal dialysis (CAPD) or automated peritoneal dialysis (APD) for the management of kidney failure in patients requiring long-term kidney replacement therapy. EXTRANEAL is also indicated to improve (compared to 4.25% dextrose) long-dwell ultrafiltration and clearance of creatinine and urea nitrogen in patients with high average or greater transport characteristics, as defined using the peritoneal equilibration test (PET) [see Clinical Pharmacology ( 12 ), Clinical Studies ( 14 )]. […]
FDA pharmacologic class: Blood Coagulation Factor, Calculi Dissolution Agent, Osmotic Laxative and Phosphate Binder.
Source: FDA drug label (EXTRANEAL), Vantive US Healthcare LLC, effective June 30, 2025 (SPL set d5b85158-b0d6-4855-9d07-8d1b3ad9ab71), via openFDA; the full label on DailyMed
Is there a generic for calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate (Extraneal)?
No generic calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate is approved (Drugs@FDA, October 8, 2026).
Source: Drugs@FDA, FDA NDC Directory and the Orange Book (openFDA bulk files, October 8, 2026)
What does the calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate label say about other medicines?
The calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate label names 1 other medicine in its interaction, contraindication or warning sections. The sentences are the labels' own; a label lists what its studies and reports found, not every interaction.
| Medicine named | Section | What the label says |
|---|---|---|
| Digoxin | drug interactions | In patients using cardiac glycosides (digoxin and others), plasma levels of calcium, potassium and magnesium must be carefully monitored [see Warnings and Precautions ( 5.6 )]. |
Source: FDA drug label (EXTRANEAL), Vantive US Healthcare LLC, effective June 30, 2025 (SPL set d5b85158-b0d6-4855-9d07-8d1b3ad9ab71), via openFDA; the full label on DailyMed
What do FAERS reports show for calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate?
The FDA Adverse Event Reporting System holds 30,880 reports that list calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate among the medicines taken, through July 30, 2026, each a report of something that happened, not proof the medicine caused it; 10,042 are coded as a death and 14,520 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is. Reports rose sharply in 2016 (3,141, against a median of 773 a year): FAERS counts follow reporting, which news, litigation and label changes can drive, not how often a reaction happens.
Reports received each year
The most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026
What next?
- Other blood coagulation factors
- the pharmacologic class, with prices and generics
- Calcium chloride, icodextrin, magnesium chloride, sodium chloride and sodium lactate side effects
- the label's list beside FAERS reports
- Check an interaction
- what two or more labels say about each other