Voriconazole and Alosetron Interaction
Drug interaction information between Voriconazole and Alosetron.
Voriconazole and Alosetron have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Voriconazole and Alosetron. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Voriconazole can slow down how your body processes alosetron, potentially causing the medication to build up in your system.
FDA Label Information
Coadministration of alosetron and strong CYP3A4 inhibitors such as clarithromycin, telithromycin, protease inhibitors, voriconazole, and itraconazole has not been evaluated but should be undertaken with caution because of similar potential drug interactions.
Voriconazole Also Interacts With
- Norethindrone major
- Rifampin major
- Lurasidone major
- Pimozide major
- Ivabradine major
Alosetron Also Interacts With
- Clarithromycin moderate
- Itraconazole moderate
- Estradiol minor
- Hydralazine minor
- Ketoconazole minor
Frequently Asked Questions
What SPL severity band is on file for Voriconazole + Alosetron?
Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Voriconazole has 50 labeled pairs on file vs Alosetron's 12. In the moderate band specifically: Voriconazole has 9 (also Tretinoin, Midazolam, Lemborexant, Darunavir); Alosetron has 3 (also Clarithromycin, Itraconazole).
What mechanism field is on file for Voriconazole and Alosetron?
Voriconazole can slow down how your body processes alosetron, potentially causing the medication to build up in your system.
Voriconazole carries more major-labeled pairs than Alosetron
SPL source-record counts only. This page's band is moderate · classes on file: Voriconazole (Azole Antifungal); Alosetron (5-HT3 Antagonist (IBS-D)).
Voriconazole has 8 major-labeled pairs vs Alosetron's 0. This page itself is in the moderate band, not the major band.
8 major · 9 moderate · 33 minor · 50 total
- Other moderate peers for Voriconazole
- Tretinoin
- Midazolam
- Lemborexant
- Darunavir
0 major · 3 moderate · 9 minor · 12 total
- Other moderate peers for Alosetron
- Clarithromycin
- Itraconazole
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.