What the FDA labels say about taking them together
Alosetron and itraconazole
Alosetron's FDA label of March 23, 2026 names itraconazole in its drug interactions section; the itraconazole labels PlainMeds reads (2) do not name alosetron.
Check it at the source: the alosetron FDA label on DailyMed (effective March 23, 2026, Legacy Pharma USA Inc.); the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.).
What does the alosetron label say about itraconazole?
Alosetron label, drug interactionsCoadministration of alosetron and strong CYP3A4 inhibitors such as clarithromycin, telithromycin, protease inhibitors, voriconazole, and itraconazole has not been evaluated but should be undertaken with caution because of similar potential drug interactions.
Source: FDA drug label (LOTRONEX), Legacy Pharma USA Inc., effective March 23, 2026 (SPL set c216e967-436f-475a-8e6a-2ad11adc63af), via openFDA; the full label on DailyMed
What does the itraconazole label say about alosetron?
Itraconazole's label (effective July 13, 2026) and its 1 other brand-application label do not name alosetron in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Alosetron | Itraconazole | |
|---|---|---|
| Labeled for | n/a | Fungal infections |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $2.02 per tablet 0.5 mg tablet | $0.910 per capsule 100 mg capsule |
| Shortage now | No current entry | A presentation being discontinued |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once