Alosetron and Hydralazine Interaction
Drug interaction information between Alosetron and Hydralazine.
Alosetron and Hydralazine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Alosetron and Hydralazine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Alosetron may interfere with the way your body processes hydralazine, potentially leading to higher drug levels.
FDA Label Information
Although not studied with alosetron, inhibition of N-acetyltransferase may have clinically relevant consequences for drugs such as isoniazid, procainamide, and hydralazine.
Alosetron Also Interacts With
- Clarithromycin moderate
- Itraconazole moderate
- Voriconazole moderate
- Estradiol minor
- Ketoconazole minor
Frequently Asked Questions
What SPL severity band is on file for Alosetron + Hydralazine?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Alosetron has 12 labeled pairs on file vs Hydralazine's 3. In the minor band specifically: Alosetron has 9 (also Estradiol, Ketoconazole, Theophylline, Cimetidine); Hydralazine has 3 (also Enalapril, Pindolol).
What mechanism field is on file for Alosetron and Hydralazine?
Alosetron may interfere with the way your body processes hydralazine, potentially leading to higher drug levels.
Alosetron's labeled portfolio outnumbers Hydralazine
SPL source-record counts only. This page's band is minor · classes on file: Alosetron (5-HT3 Antagonist (IBS-D)); Hydralazine (Vasodilator).
0 major · 3 moderate · 9 minor · 12 total
- Other minor peers for Alosetron
- Estradiol
- Ketoconazole
- Theophylline
- Cimetidine
0 major · 0 moderate · 3 minor · 3 total
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.