Perindopril and Gentamicin Interaction
Drug interaction information between Perindopril and Gentamicin.
Perindopril and Gentamicin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Perindopril and Gentamicin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Research in animals suggests these two drugs might interact, although the exact way they affect humans is not yet fully understood.
FDA Label Information
7.6 Gentamicin Animal data have suggested the possibility of interaction between perindopril and gentamicin.
Perindopril Also Interacts With
- Aliskiren major
- Spironolactone moderate
- Cyclosporine moderate
- Amiloride moderate
- Indomethacin moderate
Gentamicin Also Interacts With
- Cidofovir major
- Bictegravir/Emtricitabine/Tenofovir minor
- Digoxin minor
- Emtricitabine/Tenofovir minor
- Piperacillin/Tazobactam minor
Frequently Asked Questions
What SPL severity band is on file for Perindopril + Gentamicin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Perindopril has 9 labeled pairs on file vs Gentamicin's 7. In the minor band specifically: Perindopril has 3 (also Lithium, Digoxin); Gentamicin has 6 (also Bictegravir, Digoxin, Emtricitabine/Tenofovir, Piperacillin/Tazobactam).
What mechanism field is on file for Perindopril and Gentamicin?
Research in animals suggests these two drugs might interact, although the exact way they affect humans is not yet fully understood.
Perindopril's labeled portfolio outnumbers Gentamicin
SPL source-record counts only. This page's band is minor · classes on file: Perindopril (ACE Inhibitor); Gentamicin (Aminoglycoside Antibiotic).
1 major · 5 moderate · 3 minor · 9 total
1 major · 0 moderate · 6 minor · 7 total
- Other minor peers for Gentamicin
- Bictegravir
- Digoxin
- Emtricitabine/Tenofovir
- Piperacillin/Tazobactam
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.