PlainMeds provides educational information only. This is not medical advice. Always consult your doctor or pharmacist.

gentamicin vs perindopril

Side-by-side comparison of gentamicin and perindopril. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

7.6 Gentamicin Animal data have suggested the possibility of interaction between perindopril and gentamicin.

Recommendation: Your doctor should monitor you closely for any unusual side effects if you are prescribed both medications.

Drug Class
gentamicin Aminoglycoside Antibiotic
perindopril ACE Inhibitor
Type
gentamicin Prescription
perindopril Prescription
Summary
gentamicin

Gentamicin is an antibiotic medicine. It fights serious infections caused by certain bacteria.

perindopril

Perindopril (Aceon) is a drug that lowers blood pressure. It can also help reduce the risk of heart problems in people with stable coronary artery disease.

What It Treats
gentamicin

Gentamicin treats serious infections caused by certain bacteria. This includes infections in the blood, brain (meningitis), urinary tract, lungs, stomach area, skin, bone, and soft tissues. It can also treat bacterial infections in newborns.

perindopril

Perindopril treats high blood pressure (hypertension). It can be used alone or with other blood pressure medicines. Perindopril also helps lower the risk of heart-related death or heart attack in people who have stable coronary artery disease. It can be used with other treatments for coronary artery disease.

How It Works
gentamicin

Gentamicin belongs to a class of drugs called aminoglycoside antibiotics. It works by stopping the growth of bacteria. This helps your body fight off the infection.

perindopril

Perindopril belongs to a class of drugs called ACE inhibitors. It works by relaxing your blood vessels, which lowers blood pressure. This makes it easier for your heart to pump blood.

Common Side Effects
gentamicin

No common side effects listed.

perindopril
  • Cough
  • Dizziness
  • Back pain
FAERS Reports
gentamicin
  • Acute Kidney Injury 999
  • Pyrexia 751
  • Renal Failure 603
  • Diarrhoea 460
  • Sepsis 427
perindopril

No adverse event reports.

Serious Warnings
gentamicin

Gentamicin can potentially damage kidneys and cause nerve damage, including hearing loss. The risk is higher if you have kidney problems, receive high doses, or take it for a long time. Tell your doctor right away if you notice dizziness, ringing in your ears, changes in hearing, or kidney problems.

perindopril

If you become pregnant, stop taking perindopril right away. This medicine can cause serious harm or death to an unborn baby.

Pregnancy
gentamicin

Tell your doctor if you are pregnant or breastfeeding. Gentamicin may harm your unborn baby. It is not known if gentamicin passes into breast milk.

perindopril

Do not take perindopril if you are pregnant. It can cause harm to your unborn baby, especially during the second and third trimesters. It is not known if perindopril passes into breast milk, so talk to your doctor before breastfeeding.

Also Compare, Nearby Drugs

How to Read This gentamicin vs perindopril Comparison

gentamicin is classified in the Aminoglycoside Antibiotic drug class, while perindopril sits within the ACE Inhibitor class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, gentamicin has 3,240 submissions while perindopril has 0. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to research in animals suggests these two drugs might interact, although the exact way they affect humans is not yet fully understood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between gentamicin and perindopril - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.