What the FDA labels say about taking them together
Lithium and perindopril
Perindopril's FDA label of March 13, 2024 names lithium in its drug interactions section; the lithium labels PlainMeds reads (4) do not name perindopril. The perindopril label: “Hyperkalemia. Lithium: Increase serum lithium levels, symptoms of lithium toxicity.”
Check it at the source: the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA); the perindopril FDA label on DailyMed (effective March 13, 2024, Aurobindo Pharma Limited).
What does the lithium label say about perindopril?
Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name perindopril in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed
What does the perindopril label say about lithium?
Perindopril label, drug interactionsHyperkalemia. (7.2) Lithium: Increase serum lithium levels, symptoms of lithium toxicity.
Source: FDA drug label (Perindopril Erbumine), Aurobindo Pharma Limited, effective March 13, 2024 (SPL set 87768fbf-7c63-47da-8925-0316f343d6ef), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Lithium | Perindopril | |
|---|---|---|
| Labeled for | Bipolar disorder | High blood pressure, Heart attack and coronary artery disease |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.104 per capsule 300 mg capsule | $0.495 per tablet 4 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once