Bazedoxifene and Atorvastatin Interaction

Drug interaction information between Bazedoxifene and Atorvastatin.

Bazedoxifene and Atorvastatin have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Bazedoxifene and Atorvastatin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Bazedoxifene

SERM / Estrogen Combination

Drug B

Atorvastatin

HMG-CoA Reductase Inhibitor (Statin)

How They Interact

Studies show that these two medicines do not significantly change how the body processes each drug.

FDA Label Information

7.3 Atorvastatin Concomitant administration of bazedoxifene (40 mg daily) and atorvastatin (20 mg, single-dose) to healthy postmenopausal women did not affect the pharmacokinetics of bazedoxifene, atorvastatin or its active metabolites.

Frequently Asked Questions

What SPL severity band is on file for Bazedoxifene/Conjugated Estrogens + Atorvastatin?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Atorvastatin has 36 labeled pairs on file vs Bazedoxifene's 7. In the minor band specifically: Bazedoxifene has 7 (also Carbamazepine, Rifampin, Itraconazole, Phenytoin); Atorvastatin has 25 (also Estradiol, Norethindrone, Ketoconazole, Erythromycin).

What mechanism field is on file for Bazedoxifene/Conjugated Estrogens and Atorvastatin?

Studies show that these two medicines do not significantly change how the body processes each drug.

Atorvastatin carries more major-labeled pairs than Bazedoxifene

SPL source-record counts only. This page's band is minor · classes on file: Bazedoxifene (SERM / Estrogen Combination); Atorvastatin (HMG-CoA Reductase Inhibitor (Statin)).

Atorvastatin has 3 major-labeled pairs vs Bazedoxifene's 0. This page itself is in the minor band, not the major band.

Bazedoxifene

0 major · 0 moderate · 7 minor · 7 total

Atorvastatin

3 major · 8 moderate · 25 minor · 36 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.