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What the FDA labels say about taking them together

Atorvastatin and norethindrone

Atorvastatin's FDA label of April 15, 2024 names norethindrone in its drug interactions section; the norethindrone labels PlainMeds reads (2) do not name atorvastatin. The atorvastatin label: “Oral Contraceptives: May increase plasma levels of norethindrone and ethinyl estradiol; consider this effect when selecting an oral contraceptive.”

Check it at the source: the atorvastatin FDA label on DailyMed (effective April 15, 2024, Viatris Specialty LLC); the norethindrone FDA label on DailyMed (effective January 31, 2026, Glenmark Pharmaceuticals Inc., USA).

What does the atorvastatin label say about norethindrone?

Atorvastatin label, drug interactions

Oral Contraceptives: May increase plasma levels of norethindrone and ethinyl estradiol; consider this effect when selecting an oral contraceptive ( 7.3 ).

Source: FDA drug label (Lipitor), NDA020702 (Upjohn), as published by Viatris Specialty LLC, effective April 15, 2024 (SPL set a60cc18b-0631-4cf0-b021-9f52224ece65), via openFDA; the full label on DailyMed

What does the norethindrone label say about atorvastatin?

Norethindrone's label (effective January 31, 2026) and its 1 other brand-application label do not name atorvastatin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Norethindrone), Glenmark Pharmaceuticals Inc., USA, effective January 31, 2026 (SPL set 0d2f8fea-3675-40d2-afd9-9fcb148dbd4b), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

59Atorvastatin generic labelers
18Norethindrone generic labelers
AtorvastatinNorethindrone
Labeled forHigh cholesterol, Angina, High triglycerides, Heart attack and coronary artery diseaseBirth control
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0228 per tablet 10 mg tablet$0.290 per tablet 5 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?