Side effects across medicines
Medicines whose labels list confusional state
109 medicines have an FDA label that names confusional state in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of confusional state name pregabalin (7,077), oxycodone (6,282) and pimavanserin (4,287), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.
Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.
Which medicines' labels list confusional state?
Ordered by where the label names it, the boxed warning first, then by FAERS reports. A medicine whose own indications name it, because it treats it, is not counted.
| Medicine | Where a label names it | FAERS reports of confusional state |
|---|---|---|
| Baclofen | warnings and precautions (intrathecal label) | 1,766 |
| Cimetidine | precautions | 114 |
| Avapritinib | warnings and precautions | none in the top 1,000 |
| Mosunetuzumab | warnings and precautions (intravenous label) | none in the top 1,000 |
| Nortriptyline | precautions | none in the top 1,000 |
| Trimipramine | precautions | none in the top 1,000 |
| Pregabalin | adverse reactions | 7,077 |
| Oxycodone | adverse reactions | 6,282 |
| Pimavanserin | adverse reactions | 4,287 |
| Alprazolam | adverse reactions | 3,998 |
| Sertraline | adverse reactions | 2,847 |
| Levetiracetam | adverse reactions | 2,585 |
| Risperidone | adverse reactions | 2,469 |
| Carbidopa and levodopa | adverse reactions (enteral label) | 2,160 |
| Mycophenolate mofetil | adverse reactions | 1,833 |
| Morphine | adverse reactions | 1,831 |
| Fentanyl | adverse reactions (transdermal label) | 1,747 |
| Buprenorphine | adverse reactions (transdermal label) | 1,603 |
| Duloxetine | adverse reactions | 1,443 |
| Cyclophosphamide | adverse reactions | 1,092 |
| Hydromorphone | adverse reactions | 976 |
| Clarithromycin | adverse reactions | 785 |
| Haloperidol | adverse reactions (intramuscular label) | 764 |
| Pomalidomide | adverse reactions | 738 |
| Dalfampridine | adverse reactions | 696 |
| Lacosamide | adverse reactions | 636 |
| Oxybutynin | adverse reactions | 497 |
| Amitriptyline | adverse reactions | 405 |
| Cabozantinib | adverse reactions | 404 |
| Moxifloxacin | adverse reactions | 388 |
| Clobazam | adverse reactions | 343 |
| Thalidomide | adverse reactions | 343 |
| Fesoterodine | adverse reactions | 340 |
| Tapentadol | adverse reactions | 296 |
| Ifosfamide | adverse reactions | 248 |
| Amisulpride | adverse reactions | 245 |
| Selinexor | adverse reactions | 236 |
| Blinatumomab | adverse reactions | 230 |
| Niraparib | adverse reactions | 206 |
| Ziconotide | adverse reactions | 205 |
| Amiodarone | adverse reactions | 159 |
| Calcium oxybate, magnesium oxybate, potassium oxybate and sodium oxybate | adverse reactions | 158 |
| Dicyclomine | adverse reactions | 152 |
| Cenobamate | adverse reactions | 147 |
| Lorlatinib | adverse reactions | 134 |
| Nilotinib | adverse reactions | 134 |
| Valganciclovir | adverse reactions | 134 |
| Ranolazine | adverse reactions | 130 |
| Dichlorphenamide | adverse reactions | 126 |
| Opicapone | adverse reactions | 120 |
| Loxapine | adverse reactions | 112 |
| Triazolam | adverse reactions | 106 |
| Itraconazole | adverse reactions | 98 |
| Ganciclovir | adverse reactions | 96 |
| Perampanel | adverse reactions | 92 |
| Aldesleukin | adverse reactions | none in the top 1,000 |
| Almotriptan | adverse reactions | none in the top 1,000 |
| Amitriptyline and perphenazine | adverse reactions | none in the top 1,000 |
| Amoxicillin and clarithromycin and lansoprazole | adverse reactions | none in the top 1,000 |
| Anidulafungin | adverse reactions | none in the top 1,000 |
| Avibactam and aztreonam | adverse reactions | none in the top 1,000 |
| Bupropion and dextromethorphan | adverse reactions | none in the top 1,000 |
| Caspofungin | adverse reactions | none in the top 1,000 |
| Cilastatin and imipenem and relebactam | adverse reactions | none in the top 1,000 |
| Cytarabine and daunorubicin | adverse reactions | none in the top 1,000 |
| Dasatinib | adverse reactions | none in the top 1,000 |
| Decitabine | adverse reactions | none in the top 1,000 |
| Delafloxacin | adverse reactions | none in the top 1,000 |
| Denileukin diftitox | adverse reactions | none in the top 1,000 |
| Desipramine | adverse reactions | none in the top 1,000 |
| Dexmedetomidine | adverse reactions | none in the top 1,000 |
| Difelikefalin | adverse reactions | none in the top 1,000 |
| Elranatamab | adverse reactions | none in the top 1,000 |
| Entrectinib | adverse reactions | none in the top 1,000 |
| Epcoritamab | adverse reactions | none in the top 1,000 |
| Esketamine | adverse reactions | none in the top 1,000 |
| Esmolol | adverse reactions | none in the top 1,000 |
| Etravirine | adverse reactions | none in the top 1,000 |
| Famciclovir | adverse reactions | none in the top 1,000 |
| Gabapentin enacarbil | adverse reactions | none in the top 1,000 |
| Gepirone | adverse reactions | none in the top 1,000 |
| Hydrochlorothiazide and metoprolol | adverse reactions | none in the top 1,000 |
| Iloperidone | adverse reactions | none in the top 1,000 |
| Imipramine | adverse reactions | none in the top 1,000 |
| Iohexol | adverse reactions | none in the top 1,000 |
| Iomeprol | adverse reactions | none in the top 1,000 |
| Iopamidol | adverse reactions | none in the top 1,000 |
| Isavuconazonium | adverse reactions | none in the top 1,000 |
| Lapine t-lymphocyte immune globulin | adverse reactions | none in the top 1,000 |
| Larotrectinib | adverse reactions | none in the top 1,000 |
| Milsaperidone | adverse reactions | none in the top 1,000 |
| Narsoplimab | adverse reactions | none in the top 1,000 |
| Nelarabine | adverse reactions | none in the top 1,000 |
| Paricalcitol | adverse reactions (intravenous label) | none in the top 1,000 |
| Pexidartinib | adverse reactions | none in the top 1,000 |
| Pirtobrutinib | adverse reactions | none in the top 1,000 |
| Polidocanol | adverse reactions (intravenous label) | none in the top 1,000 |
| Porfimer | adverse reactions | none in the top 1,000 |
| Protriptyline | adverse reactions | none in the top 1,000 |
| Repotrectinib | adverse reactions | none in the top 1,000 |
| Sodium benzoate and sodium phenylacetate | adverse reactions | none in the top 1,000 |
| Talquetamab | adverse reactions | none in the top 1,000 |
| Tarlatamab-dlle | adverse reactions | none in the top 1,000 |
| Teclistamab | adverse reactions | none in the top 1,000 |
| Thioridazine | adverse reactions | none in the top 1,000 |
| Treosulfan | adverse reactions | none in the top 1,000 |
| Vigabatrin | adverse reactions | none in the top 1,000 |
| Zuranolone | adverse reactions | none in the top 1,000 |
| Amantadine | trial table | 623 |
Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026
Which of them have the most confusional state reports in FAERS?
Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Confusional State”
What next?
- Side effects across medicines
- every reaction on PlainMeds
- Report a side effect to the FDA
- MedWatch