Side effects across medicines

Medicines whose labels list chills

469 medicines have an FDA label that names chills in its boxed warning, warnings, adverse reactions, trial table, patient leaflet or Drug Facts “stop use” warning (of the labels PlainMeds reads: each medicine's quoted label and up to eight more, by route and wording). Among them, the most FAERS reports of chills name adalimumab (4,831), diphenhydramine (3,906) and omeprazole (3,641), through July 30, 2026. A label lists what its studies and reports found, and a report does not show that a medicine caused the event.

Check it at the source: the FDA FAERS public dashboard; FDA labels on DailyMed.

Which medicines' labels list chills?

Ordered by where the label names it, the boxed warning first, then by FAERS reports. The first 152 of the 469 are below; every other one is on its medicine record. A medicine whose own indications name it, because it treats it, is not counted.

Medicine	Where a label names it	FAERS reports of chills
Obinutuzumab	warnings and precautions	499
Fludarabine	precautions	285
Rifampin	precautions	109
Alanine, arginine and 15 other ingredients	warnings and precautions	none in the top 1,000
Anti-inhibitor coagulant complex	warnings and precautions	none in the top 1,000
Axatilimab	warnings and precautions	none in the top 1,000
Bacillus calmette-guerin substrain tice live antigen	precautions	none in the top 1,000
Daratumumab	warnings and precautions	none in the top 1,000
Mogamulizumab	warnings and precautions	none in the top 1,000
Procainamide	precautions	none in the top 1,000
Raxibacumab	warnings and precautions	none in the top 1,000
Trastuzumab-strf	warnings and precautions	none in the top 1,000
Vinblastine	precautions	none in the top 1,000
Diphenhydramine	adverse reactions	3,906
Ofatumumab	adverse reactions	3,483
Methotrexate	adverse reactions	3,473
Interferon beta 1a	adverse reactions (intramuscular label)	3,455
Rituximab	adverse reactions	2,483
Infliximab	adverse reactions	2,068
Simvastatin	adverse reactions	2,055
Lorazepam	adverse reactions (intramuscular/intravenous label)	1,778
Sodium chloride	adverse reactions	1,769
Glatiramer	adverse reactions	1,402
Cyclophosphamide	adverse reactions	1,380
Trastuzumab	adverse reactions	1,355
Dabrafenib	adverse reactions	1,332
Trametinib	adverse reactions	1,293
Zoledronic acid	adverse reactions	1,293
Venlafaxine	adverse reactions	1,259
Fluoxetine	adverse reactions	1,211
Oxycodone	adverse reactions	1,076
Sulfamethoxazole and trimethoprim	adverse reactions	1,009
Dextrose and potassium chloride	adverse reactions	942
Baclofen	adverse reactions (intrathecal label)	893
Mirtazapine	adverse reactions	846
Human immunoglobulin g	adverse reactions	839
Sildenafil	adverse reactions	816
Warfarin	adverse reactions	769
Fentanyl	adverse reactions	744
Lamotrigine	adverse reactions	734
Paclitaxel	adverse reactions	725
Tacrolimus	adverse reactions	725
Mycophenolate mofetil	adverse reactions	710
Bupropion	adverse reactions	707
Hydromorphone	adverse reactions	675
Vancomycin	adverse reactions	663
Interferon beta 1b	adverse reactions	596
Cetuximab	adverse reactions	575
Doxorubicin	adverse reactions	566
Morphine	adverse reactions	516
Exenatide	adverse reactions	515
Alemtuzumab	adverse reactions	496
Duloxetine	adverse reactions	494
Ibrutinib	adverse reactions	478
Agalsidase beta	adverse reactions	476
Gemcitabine	adverse reactions	469
Sofosbuvir	adverse reactions	469
Buprenorphine	adverse reactions	464
Olanzapine	adverse reactions	442
Propofol	adverse reactions	414
Etoposide	adverse reactions	380
Everolimus	adverse reactions	374
Carbamazepine	adverse reactions	372
Paroxetine	adverse reactions	354
Nilotinib	adverse reactions	353
Pomalidomide	adverse reactions	351
Iohexol	adverse reactions	347
Leuprolide	adverse reactions	344
Peginterferon beta 1a	adverse reactions	333
Nitrofurantoin	adverse reactions	330
Piperacillin and tazobactam	adverse reactions	329
Ceftriaxone	adverse reactions	327
Sunitinib	adverse reactions	306
Varenicline	adverse reactions	302
Dexlansoprazole	adverse reactions	292
Pravastatin	adverse reactions	287
Meropenem	adverse reactions	269
Naltrexone	adverse reactions	268
Nifedipine	adverse reactions	255
Fluvastatin	adverse reactions	254
Clarithromycin	adverse reactions	252
Epoprostenol	adverse reactions	251
Modafinil	adverse reactions	248
Lecanemab	adverse reactions	241
Buprenorphine and naloxone	adverse reactions	237
Aprepitant	adverse reactions (intravenous label)	226
Divalproex	adverse reactions	221
Bendamustine	adverse reactions	220
Lovastatin	adverse reactions	196
Carfilzomib	adverse reactions	195
Hydroxyurea	adverse reactions	179
Atomoxetine	adverse reactions	178
Desvenlafaxine	adverse reactions	178
Dextrose	adverse reactions	178
Epoetin	adverse reactions	174
Misoprostol	adverse reactions	160
Thalidomide	adverse reactions	160
Voriconazole	adverse reactions	156
Ifosfamide	adverse reactions	153
Cefuroxime	adverse reactions	141
Medroxyprogesterone	adverse reactions (intramuscular label)	139
Midazolam	adverse reactions	139
Lapine t-lymphocyte immune globulin	adverse reactions	134
Soybean oil	adverse reactions	134
Iopromide	adverse reactions	133
Moxifloxacin	adverse reactions	127
Niacin	adverse reactions	127
Brentuximab vedotin	adverse reactions	124
Panitumumab	adverse reactions	123
Amphotericin b	adverse reactions	120
Degarelix	adverse reactions	119
Valganciclovir	adverse reactions	116
Irinotecan	adverse reactions	115
Albumin human	adverse reactions	114
Ezetimibe and simvastatin	adverse reactions	114
Asfotase alfa	adverse reactions	112
Naloxegol	adverse reactions	112
Trastuzumab emtansine	adverse reactions	112
Bleomycin	adverse reactions	111
Eltrombopag	adverse reactions	111
Ascorbic acid, polyethylene glycol 3350 and 4 other ingredients	adverse reactions	110
Itraconazole	adverse reactions	110
Posaconazole	adverse reactions	110
Trazodone	adverse reactions	110
Heparin	adverse reactions	109
Bicalutamide	adverse reactions	107
Diclofenac and misoprostol	adverse reactions	104
Lamivudine	adverse reactions	103
Blinatumomab	adverse reactions	102
Iodixanol	adverse reactions	99
Ketoconazole	adverse reactions (oral label)	97
Hydrocodone	adverse reactions	96
Valproic acid	adverse reactions	95
Idursulfase	adverse reactions	92
Oritavancin	adverse reactions	92
Doxepin	adverse reactions	91
Pazopanib	adverse reactions	91
Hydrochlorothiazide and lisinopril	adverse reactions	86
Metolazone	adverse reactions	85
Cabotegravir	adverse reactions	83
Ravulizumab	adverse reactions	80
Elosulfase alfa	adverse reactions	77
Ferric carboxymaltose	adverse reactions	76
Dronabinol	adverse reactions	75
Ertapenem	adverse reactions	75
Goserelin	adverse reactions	73
Talimogene laherparepvec	adverse reactions	73
Axitinib	adverse reactions	71
Amifostine	adverse reactions	69
Bupivacaine	adverse reactions	69
Adalimumab	patient leaflet	4,831
Omeprazole	patient leaflet	3,641

Source: FDA drug labels via openFDA, read October 8, 2026; FAERS via openFDA, reports through July 30, 2026

Which of them have the most chills reports in FAERS?

Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is.

Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; MedDRA preferred term “Chills”

What next?

Side effects across medicines: every reaction on PlainMeds
Report a side effect to the FDA: MedWatch