Nicardipine and Warfarin Interaction

Drug interaction information between Nicardipine and Warfarin.

Nicardipine and Warfarin have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Nicardipine and Warfarin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Nicardipine

Calcium Channel Blocker

Drug B

Warfarin

Vitamin K Antagonist (Anticoagulant)

How They Interact

Warfarin does not interfere with the way nicardipine attaches to blood proteins.

FDA Label Information

When therapeutic concentrations of furosemide, propranolol, dipyridamole, warfarin, quinidine or naproxen were added to human plasma (in vitro), the plasma protein binding of nicardipine hydrochloride capsules were not altered.

Warfarin Also Interacts With

View all Warfarin interactions →

Frequently Asked Questions

What SPL severity band is on file for Nicardipine + Warfarin?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Warfarin has 163 labeled pairs on file vs Nicardipine's 14. In the minor band specifically: Nicardipine has 11 (also Furosemide, Propranolol, Naproxen, Cyclosporine); Warfarin has 133 (also Atorvastatin, Amlodipine, Omeprazole, Famotidine).

What mechanism field is on file for Nicardipine and Warfarin?

Warfarin does not interfere with the way nicardipine attaches to blood proteins.

Warfarin carries more major-labeled pairs than Nicardipine

SPL source-record counts only. This page's band is minor · classes on file: Nicardipine (Calcium Channel Blocker); Warfarin (Vitamin K Antagonist (Anticoagulant)).

Warfarin has 2 major-labeled pairs vs Nicardipine's 1. This page itself is in the minor band, not the major band.

Nicardipine

1 major · 2 moderate · 11 minor · 14 total

Warfarin

2 major · 28 moderate · 133 minor · 163 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.