What the FDA labels say about taking them together
Cyclosporine and nicardipine
Cyclosporine's FDA label of August 10, 2026 names nicardipine in its drug interactions section, and nicardipine's label names cyclosporine too. The nicardipine label: “Oral or intravenous nicardipine may increase cyclosporine and tacrolimus plasma levels.”
Check it at the source: the cyclosporine FDA label on DailyMed (effective August 10, 2026, Novartis Pharmaceuticals Corporation); the nicardipine FDA label on DailyMed (effective August 24, 2024, Hikma Pharmaceuticals USA Inc.).
What does the cyclosporine label say about nicardipine?
Cyclosporine label, drug interactionsnicardipine; itraconazole; clarithromycin; Amiodarone
Source: FDA drug label (Neoral), Novartis Pharmaceuticals Corporation, effective August 10, 2026 (SPL set 94461af3-11f1-4670-95d4-2965b9538ae3), via openFDA; the full label on DailyMed
What does the nicardipine label say about cyclosporine?
Nicardipine label, drug interactionsDRUG INTERACTIONS Cimetidine increases nicardipine plasma levels ( 7.3 ). Nicardipine may increase cyclosporine and tacrolimus plasma levels.
Cardene Iv label (Baxter Healthcare Corporation, April 13, 2026), drug interactionsOral or intravenous nicardipine may increase cyclosporine and tacrolimus plasma levels.
Source: FDA drug label (Cardene Iv, NDA019734), Baxter Healthcare Corporation, effective April 13, 2026 (SPL set a3e33add-0d09-423a-9109-42e5ba7148d5), via openFDA
Source: FDA drug label (Nicardipine Hydrochloride), Hikma Pharmaceuticals USA Inc., effective August 24, 2024 (SPL set 18fb1c2b-0c1e-436c-a5b6-d4840b5da228), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Cyclosporine | Nicardipine | |
|---|---|---|
| Labeled for | Organ transplant rejection, Rheumatoid arthritis | High blood pressure, Angina |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $1.04 per unit 0.05% eye emulsion | $1.12 per capsule 20 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once