Nicardipine and Furosemide Interaction
Drug interaction information between Nicardipine and Furosemide.
Nicardipine and Furosemide have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Nicardipine and Furosemide. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These drugs do not interfere with how nicardipine attaches to proteins in the blood.
FDA Label Information
When therapeutic concentrations of furosemide, propranolol, dipyridamole, warfarin, quinidine or naproxen were added to human plasma (in vitro), the plasma protein binding of nicardipine hydrochloride capsules were not altered.
Nicardipine Also Interacts With
- Digoxin major
- Nirmatrelvir/Ritonavir moderate
- Tacrolimus Topical moderate
- Propranolol minor
- Naproxen minor
Furosemide Also Interacts With
- Dutasteride major
- Dutasteride/Tamsulosin major
- Tamsulosin major
- Cyclosporine moderate
- Lithium moderate
Frequently Asked Questions
What SPL severity band is on file for Nicardipine + Furosemide?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Furosemide has 36 labeled pairs on file vs Nicardipine's 14. In the minor band specifically: Nicardipine has 11 (also Propranolol, Naproxen, Warfarin, Cyclosporine); Furosemide has 29 (also Methotrexate, Norepinephrine, Ethacrynic Acid, Indomethacin).
What mechanism field is on file for Nicardipine and Furosemide?
These drugs do not interfere with how nicardipine attaches to proteins in the blood.
Furosemide carries more major-labeled pairs than Nicardipine
SPL source-record counts only. This page's band is minor · classes on file: Nicardipine (Calcium Channel Blocker); Furosemide (Loop Diuretic).
Furosemide has 3 major-labeled pairs vs Nicardipine's 1. This page itself is in the minor band, not the major band.
1 major · 2 moderate · 11 minor · 14 total
- Other minor peers for Nicardipine
- Propranolol
- Naproxen
- Warfarin
- Cyclosporine
3 major · 4 moderate · 29 minor · 36 total
- Other minor peers for Furosemide
- Methotrexate
- Norepinephrine
- Ethacrynic Acid
- Indomethacin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.