What the label lists and what reports show
Hydrochlorothiazide and triamterene side effects
Hydrochlorothiazide and triamterene's FDA label lists its adverse reactions in its own words. FAERS holds 6,109 reports naming it through July 30, 2026; the reaction reported most often, leaving out the conditions it is used for, product-use terms and outcomes, is nausea (407 reports).
- Generic listed
Check it at the source: the hydrochlorothiazide and triamterene FDA label on DailyMed (effective February 17, 2026, Apotex Corp.); the FDA FAERS public dashboard.
What does the label list?
From the label: adverse reactionsSide effects observed in association with the use of triamterene and hydrochlorothiazide tablets, other combination products containing triamterene/hydrochlorothiazide, and products containing triamterene or hydrochlorothiazide include the following: Gastrointestinal: jaundice (intrahepatic cholestatic jaundice), pancreatitis, nausea, appetite disturbance, taste alteration, vomiting, diarrhea, constipation, anorexia, gastric irritation, cramping. Central Nervous System: drowsiness and fatigue, insomnia, headache, dizziness, dry mouth, depression, anxiety, vertigo, restlessness, paresthesias. Cardiovascular: tachycardia, shortness of breath and chest pain, orthostatic hypotension (may be aggravated by alcohol, barbiturates or narcotics). …
Source: FDA drug label, Apotex Corp., effective February 17, 2026 (SPL set bd6c3495-ec70-908b-482a-a979506659e9), via openFDA; the full label on DailyMed
What do FAERS reports show?
6,109 reports list hydrochlorothiazide and triamterene among the medicines taken, each a report of something that happened, not proof the medicine caused it; 352 are coded as a death and 1,567 as a hospital stay. Counts follow how widely a medicine is used and watched, and they are not a measure of how risky it is. Of the 24 reactions below, 10 are named by the same term (in US spelling) in the label's adverse reactions, warnings or patient leaflet; a reaction the label does not name may still be there under another word, and a report does not show that the medicine caused it.
Reports received each year
The 25 most reported reactions
Source: FDA Adverse Event Reporting System (FAERS) via openFDA, reports through July 30, 2026; reactions as MedDRA preferred terms
What next?
- Hydrochlorothiazide and triamterene: the full record
- label, generics, price, shortages, recalls
- Report a side effect to the FDA
- MedWatch
- Side effects hub
- the most reported medicines and reactions