PlainMeds rankings

The highest NADAC prices per unit

The newest NADAC file, every description, highest per-unit price first: what retail pharmacies paid, not what a patient pays. The most: ustekinumab ($29,874.45 per unit (tablet, mL or gram)).

The ranking

Rank	Medicine	Per unit (tablet, ml or gram)
1	UstekinumabSTELARA 45 MG/0.5 ML SYRINGE	$29,874.45
2	UstekinumabSTELARA 90 MG/ML SYRINGE	$29,792.79
3	OfatumumabKESIMPTA 20 MG/0.4 ML PEN	$24,369.37
4	RisankizumabSKYRIZI 150 MG/ML SYRINGE	$22,887.44
5	RisankizumabSKYRIZI 150 MG/ML PEN	$22,774.36
6	GuselkumabTREMFYA 100 MG/ML ONE-PRESS	$14,743.72
7	GuselkumabTREMFYA 100 MG/ML SYRINGE	$14,728.91
8	GuselkumabTREMFYA 100 MG/ML PEN	$14,620.07
9	GolimumabSIMPONI 50 MG/0.5 ML SYRINGE	$12,977.24
10	GolimumabSIMPONI 50 MG/0.5 ML PEN INJEC	$12,890.32
11	RisankizumabSKYRIZI 360 MG/2.4 ML ON-BODY	$9,572.67
12	RisperidoneUZEDY ER 50 MG/0.14 ML SYRINGE	$9,451.01
13	RisperidoneUZEDY ER 100 MG/0.28 ML SYRING	$9,389.09
14	RisperidoneUZEDY ER 75 MG/0.21 ML SYRINGE	$9,358.66
15	RisperidoneUZEDY ER 200 MG/0.56 ML SYRING	$9,346.07
16	RisperidoneUZEDY ER 125 MG/0.35 ML SYRING	$9,329.00
17	Interferon beta 1aAVONEX 30 MCG/0.5 ML SYRINGE KIT (4 PACK)	$8,776.25
18	Interferon beta 1aAVONEX PEN 30 MCG/0.5 ML KIT (4 PACK)	$8,772.02
19	BimekizumabBIMZELX 160 MG/ML AUTOINJECTOR	$8,073.83
20	BimekizumabBIMZELX 320 MG/2 ML AUTOINJECT	$8,016.04
21	SecukinumabCOSENTYX 150 MG/ML SYRINGE	$7,879.81
22	SecukinumabCOSENTYX SENSOREADY 150 MG/ML PEN	$7,858.48
23	IxekizumabTALTZ 80 MG/ML AUTOINJECTOR (2-PACK)	$7,435.87
24	IxekizumabTALTZ 80 MG/ML AUTOINJECTOR (3-PACK)	$7,388.22
25	IxekizumabTALTZ 80 MG/ML AUTOINJECTOR	$7,370.72
26	GuselkumabTREMFYA 200 MG/2 ML PEN	$7,321.66
27	OctreotideSANDOSTATIN LAR DEPOT 30 MG KT	$6,948.08
28	AdalimumabHUMIRA(CF) PEN CROHN'S-UC-HS STARTER 80 MG/0.8 ML	$6,745.43
29	AdalimumabHUMIRA(CF) PEN 80 MG/0.8 ML	$6,736.72
30	CertolizumabCIMZIA 2X200 MG/ML SYRINGE KIT	$6,094.02
31	LeuprolideLUPRON DEPOT 11.25 MG 3MO KIT	$5,437.40
32	OctreotideSANDOSTATIN LAR DEPOT 20 MG KT	$4,588.55
33	PaliperidoneINVEGA HAFYERA 1,560 MG/5 ML	$4,233.40
34	SecukinumabCOSENTYX UNOREADY 300 MG/2 ML PEN (1 PEN)	$4,087.41
35	PaliperidoneINVEGA HAFYERA 1,092 MG/3.5 ML	$4,047.71
36	PaliperidoneINVEGA TRINZA 819 MG/2.63 ML	$3,997.97
37	PaliperidoneINVEGA TRINZA 546 MG/1.75 ML	$3,993.63
38	PaliperidoneINVEGA TRINZA 410 MG/1.32 ML	$3,959.46
39	PaliperidoneINVEGA TRINZA 273 MG/0.88 ML	$3,950.95
40	SecukinumabCOSENTYX SENSOREADY 300 MG DOSE/2 PENS (150 MG/PEN)	$3,946.35
41	UstekinumabSTEQEYMA 90 MG/ML SYRINGE	$3,931.99
42	SecukinumabCOSENTYX (150 MG/ML) 300 MG DOSE-2 SYRINGES	$3,924.35
43	OctreotideSANDOSTATIN LAR DEPOT 10 MG KT	$3,523.03
44	PegfilgrastimFULPHILA 6 MG/0.6 ML SYRINGE	$3,369.51
45	AdalimumabHUMIRA 40 MG/0.8 ML SYRINGE	$3,369.09
46	AdalimumabHUMIRA(CF) PEN 40 MG/0.4 ML	$3,367.41
47	AdalimumabHUMIRA(CF) 40 MG/0.4 ML SYRINGE	$3,367.18
48	AdalimumabHUMIRA PEN 40 MG/0.8 ML	$3,366.90
49	AdalimumabHUMIRA(CF) 20 MG/0.2 ML SYRINGE	$3,366.12
50	GlucagonGVOKE HYPOPEN 2PK 0.5 MG/0.1 ML	$3,202.33
51	UstekinumabYESINTEK 90 MG/ML SYRINGE	$2,902.88
52	AripiprazoleABILIFY MAINTENA ER 400 MG VL	$2,857.77
53	UstekinumabYESINTEK 45 MG/0.5 ML SYRINGE	$2,855.57
54	AripiprazoleABILIFY MAINTENA ER 400 MG SYR	$2,853.25
55	PaliperidoneINVEGA SUSTENNA 117 MG/0.75 ML	$2,339.67
56	PaliperidoneINVEGA SUSTENNA 39 MG/0.25 ML	$2,338.75
57	PaliperidoneINVEGA SUSTENNA 234 MG/1.5 ML	$2,338.47
58	PaliperidoneINVEGA SUSTENNA 156 MG/ML SYRG	$2,337.71
59	PaliperidoneINVEGA SUSTENNA 78 MG/0.5 ML	$2,337.05
60	Ethinyl estradiol and segesteroneANNOVERA VAGINAL RING	$2,315.29

Source: CMS National Average Drug Acquisition Cost (NADAC) weekly files, data.medicaid.gov, read October 8, 2026

What it cannot show

Units differ (a vial against a tablet, a mL of a concentrated syringe against a whole one); compare within a form.