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PlainMeds drug rankings

Drugs with Most Hospitalization Reports

All tracked drugs ranked by FAERS reports involving hospitalization.

Data updated 2026-05-15

524
Drugs ranked
203,341
Top: Aspirin
45,226
#50: Citalopram

In the Drugs with Most Hospitalization Reports ranking, Aspirin is #1 at 203,341 (Hospital Reports), out of 524 ranked drugs.

All tracked drugs ranked by FAERS reports involving hospitalization. Aspirin leads at 203,341, then Furosemide at 190,901. Every value is compiled live from official FDA and CMS records; see the methodology for how each figure is sourced and what it does and does not mean.

Verify with FDA → · CMS NADAC pricing →

What This Ranking Tells Us

Hospitalization reports in FAERS indicate cases where a drug-associated adverse event led to or extended a hospital stay. Widely prescribed medications naturally accumulate more reports. Blood thinners, insulin, and cardiovascular drugs often top this list because their therapeutic effects require careful dosing, too much or too little can require emergency intervention. These reports help FDA identify drugs that may benefit from improved dosing guidelines or additional monitoring requirements.

Top 12 by Hospital Reports

All tracked drugs ranked by FAERS reports involving hospitalization.

Hospital Reports

What this shows aspirin leads at 203,341, ahead of furosemide and prednisone.

Source FDA Adverse Event Reporting System (FAERS)

The bar to make this list: a drug needs 45,226 hospital reports to rank in the top 50 of 524.

# Drug Hospital Reports
1 aspirin 203,341
2 furosemide 190,901
3 prednisone 166,315
4 acetaminophen 150,224
5 adalimumab 146,638
6 omeprazole 122,601
7 metformin 122,330
8 methotrexate 115,535
9 pantoprazole 111,504
10 dexamethasone 109,720
11 amlodipine 104,040
12 gabapentin 103,305
13 rivaroxaban 102,060
14 ergocalciferol 98,409
15 metoprolol 96,962
16 lisinopril 95,486
17 simvastatin 94,740
18 clopidogrel 88,784
19 levothyroxine 88,368
20 folic acid 87,188
21 ibuprofen 81,556
22 prednisolone 79,445
23 pregabalin 74,751
24 allopurinol 74,277
25 lorazepam 72,527
26 atorvastatin 68,513
27 quetiapine 67,436
28 etanercept 65,552
29 alprazolam 64,280
30 spironolactone 64,112
31 ramipril 62,948
32 insulin glargine 62,916
33 lansoprazole 62,821
34 infliximab 62,267
35 rosuvastatin 60,611
36 warfarin 57,230
37 methylprednisolone 53,959
38 carvedilol 53,070
39 clozapine 53,005
40 oxycodone 49,832
41 losartan 48,929
42 hydrochlorothiazide 48,508
43 potassium chloride 48,372
44 levetiracetam 47,411
45 atenolol 47,314
46 ondansetron 47,077
47 clonazepam 46,031
48 olanzapine 45,342
49 zolpidem 45,304
50 citalopram 45,226

Primary source: FDA Adverse Event Reporting System (FAERS). Supplementary labeling: FDA Drug Labels (SPL). These rankings are for informational purposes only and should not be used to make medical decisions.

Frequently Asked Questions

What does a hospitalization report in FAERS mean?

It means an adverse event report included hospitalization (initial or prolonged) as a serious outcome. The hospitalization may have been caused by the drug, an underlying condition, or a combination. FAERS does not determine causality, it documents associations for FDA to investigate.

Are drugs with more hospitalization reports less safe?

Not necessarily. Drugs prescribed to millions of people or to severely ill populations will naturally have more hospitalization reports. A per-prescription hospitalization rate would be more informative. These rankings are useful for identifying which drugs require the most post-marketing surveillance.

Reading the Drugs with Most Hospitalization Reports

This table ranks 50 drugs by hospital reports, sourced from FDA Adverse Event Reporting System (FAERS). The current leader is aspirin at 203,341, followed by furosemide and prednisone. Each row links to a full drug profile so readers can move from headline number to the underlying FDA data, labeling, FAERS reports, recalls, pricing, and shortage status, that explains why a particular drug sits where it does.

Hospitalization reports in FAERS indicate cases where a drug-associated adverse event led to or extended a hospital stay. Widely prescribed medications naturally accumulate more reports. Blood thinners, insulin, and cardiovascular drugs often top this list because their therapeutic effects require careful dosing, too much or too little can require emergency intervention. These reports help FDA identify drugs that may benefit from improved dosing guidelines or additional monitoring requirements.

Rankings are diagnostic, not prescriptive. Absolute numbers are shaped by exposure volume, reporting practices, and data-collection methodology, so a drug near the top is not automatically "worse" than a drug near the bottom, it may simply be older, more widely prescribed, or manufactured by firms with more visible reporting. Context from FDA Adverse Event Reporting System (FAERS) updates continuously, which means the relative order here can change from one refresh to the next. Rankings on this page are for educational research only and must not be used as a substitute for medical advice from a licensed clinician.

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Read our methodology - how this data is sourced, computed, and verified.

Source: FDA Adverse Event Reporting System (FAERS) FDA Adverse Event Reporting System (FAERS)

See our methodology for how this data is sourced, computed, and verified.

Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled and last refreshed May 2026. See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a correction.