Ziprasidone and Propranolol Interaction
Drug interaction information between Ziprasidone and Propranolol.
Ziprasidone and Propranolol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Ziprasidone and Propranolol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Studies of patients show that these two drugs do not have a significant effect on how the body handles either medication. They do not change each other's levels in the body.
FDA Label Information
7.9 Other Concomitant Drug Therapy Population pharmacokinetic analysis of schizophrenic patients enrolled in controlled clinical trials has not revealed evidence of any clinically significant pharmacokinetic interactions with benztropine, propranolol, or lorazepam.
Ziprasidone Also Interacts With
- Buspirone moderate
- Lithium moderate
- Tetrabenazine moderate
- Estradiol minor
- Lorazepam minor
Frequently Asked Questions
What SPL severity band is on file for Ziprasidone + Propranolol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Propranolol has 44 labeled pairs on file vs Ziprasidone's 18. In the minor band specifically: Ziprasidone has 15 (also Estradiol, Lorazepam, Progesterone, Ketoconazole); Propranolol has 44 (also Clonidine, Diltiazem, Warfarin, Verapamil).
What mechanism field is on file for Ziprasidone and Propranolol?
Studies of patients show that these two drugs do not have a significant effect on how the body handles either medication. They do not change each other's levels in the body.
Propranolol's labeled portfolio outnumbers Ziprasidone
SPL source-record counts only. This page's band is minor · classes on file: Ziprasidone (Atypical Antipsychotic); Propranolol (Non-Selective Beta-Blocker).
0 major · 3 moderate · 15 minor · 18 total
- Other minor peers for Ziprasidone
- Estradiol
- Lorazepam
- Progesterone
- Ketoconazole
0 major · 0 moderate · 44 minor · 44 total
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.