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What the FDA labels say about taking them together

Doxazosin and propranolol

Propranolol's FDA label of January 15, 2026 names doxazosin in its drug interactions section; the doxazosin labels PlainMeds reads (2) do not name propranolol. The propranolol label: “Postural hypotension has been reported in patients taking both beta-blockers and terazosin or doxazosin.”

Check it at the source: the doxazosin FDA label on DailyMed (effective October 15, 2023, Viatris Specialty LLC); the propranolol FDA label on DailyMed (effective January 15, 2026, Mylan Pharmaceuticals Inc.).

What does the doxazosin label say about propranolol?

Doxazosin's label (effective October 15, 2023) and its 1 other brand-application label do not name propranolol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Cardura), Viatris Specialty LLC, effective October 15, 2023 (SPL set 5e1f5e49-2da1-43ab-9795-228a8bcc5a82), via openFDA; the full label on DailyMed

What does the propranolol label say about doxazosin?

Propranolol label, drug interactions

Postural hypotension has been reported in patients taking both beta-blockers and terazosin or doxazosin.

Source: FDA drug label (Propranolol Hydrochloride), Mylan Pharmaceuticals Inc., effective January 15, 2026 (SPL set b94dcec7-7633-4a33-9cea-48161adeaf93), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

29Doxazosin generic labelers
42Propranolol generic labelers
DoxazosinPropranolol
Labeled forEnlarged prostate (BPH), High blood pressureHigh blood pressure, Angina, Atrial fibrillation, Migraine
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0752 per tablet 1 mg tablet$0.0493 per tablet 20 mg tablet
Shortage nowNo current entryIn shortage

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?