Ramipril and Warfarin Interaction

Drug interaction information between Ramipril and Warfarin.

Ramipril and Warfarin have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Ramipril and Warfarin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Ramipril

ACE Inhibitor

Drug B

Warfarin

Vitamin K Antagonist (Anticoagulant)

How They Interact

Ramipril does not interfere with the blood-thinning effects of this medication.

FDA Label Information

The co-administration of ramipril and warfarin did not adversely affect the anticoagulation effects of the latter drug.

Ramipril Also Interacts With

View all Ramipril interactions →

Warfarin Also Interacts With

View all Warfarin interactions →

Frequently Asked Questions

What SPL severity band is on file for Ramipril + Warfarin?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Warfarin has 163 labeled pairs on file vs Ramipril's 11. In the minor band specifically: Ramipril has 7 (also Simvastatin, Furosemide, Propranolol, Digoxin); Warfarin has 133 (also Atorvastatin, Amlodipine, Omeprazole, Famotidine).

What mechanism field is on file for Ramipril and Warfarin?

Ramipril does not interfere with the blood-thinning effects of this medication.

Warfarin carries more major-labeled pairs than Ramipril

SPL source-record counts only. This page's band is minor · classes on file: Ramipril (ACE Inhibitor); Warfarin (Vitamin K Antagonist (Anticoagulant)).

Warfarin has 2 major-labeled pairs vs Ramipril's 0. This page itself is in the minor band, not the major band.

Ramipril

0 major · 4 moderate · 7 minor · 11 total

Warfarin

2 major · 28 moderate · 133 minor · 163 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.