Ramipril and Propranolol Interaction
Drug interaction information between Ramipril and Propranolol.
Ramipril and Propranolol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Ramipril and Propranolol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Taking these two drugs together does not cause any harmful changes to your heart rate or blood pressure.
FDA Label Information
The combination of ramipril and propranolol showed no adverse effects on dynamic parameters (blood pressure and heart rate).
Ramipril Also Interacts With
- Spironolactone moderate
- Telmisartan moderate
- Lithium moderate
- Amiloride moderate
- Simvastatin minor
Frequently Asked Questions
What SPL severity band is on file for Ramipril + Propranolol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Propranolol has 44 labeled pairs on file vs Ramipril's 11. In the minor band specifically: Ramipril has 7 (also Simvastatin, Furosemide, Warfarin, Digoxin); Propranolol has 44 (also Clonidine, Diltiazem, Warfarin, Verapamil).
What mechanism field is on file for Ramipril and Propranolol?
Taking these two drugs together does not cause any harmful changes to your heart rate or blood pressure.
Propranolol's labeled portfolio outnumbers Ramipril
SPL source-record counts only. This page's band is minor · classes on file: Ramipril (ACE Inhibitor); Propranolol (Non-Selective Beta-Blocker).
0 major · 4 moderate · 7 minor · 11 total
- Other minor peers for Ramipril
- Simvastatin
- Furosemide
- Warfarin
- Digoxin
0 major · 0 moderate · 44 minor · 44 total
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.