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What the FDA labels say about taking them together

Ramipril and telmisartan

Ramipril's FDA label of August 24, 2026 names telmisartan in its warnings and precautions section, and telmisartan's label names ramipril too. The ramipril label: “Patients receiving the combination of telmisartan and ramipril did not obtain any benefit in the composite endpoint of cardiovascular death, MI, stroke and heart failure hospitalization compared to monotherapy, but …”

Check it at the source: the ramipril FDA label on DailyMed (effective August 24, 2026, Lupin Pharmaceuticals, Inc.); the telmisartan FDA label on DailyMed (effective May 29, 2026, Alembic Pharmaceuticals Limited).

What does the ramipril label say about telmisartan?

Ramipril label, warnings and precautions

Patients receiving the combination of telmisartan and ramipril did not obtain any benefit in the composite endpoint of cardiovascular death, MI, stroke and heart failure hospitalization compared to monotherapy, but experienced an increased incidence of clinically important renal dysfunction (death, doubling of serum creatinine, or dialysis) compared with groups receiving telmisartan alone or ramipril alone. Concomitant use of telmisartan and ramipril is not recommended.

Source: FDA drug label (Ramipril), Lupin Pharmaceuticals, Inc., effective August 24, 2026 (SPL set a8cdec12-81d1-4ef4-82c0-d05d93c37a07), via openFDA; the full label on DailyMed

What does the telmisartan label say about ramipril?

Telmisartan label, warnings and precautions

Patients receiving the combination of telmisartan and ramipril did not obtain any additional benefit compared to monotherapy, but experienced an increased incidence of renal dysfunction (e.g., acute renal failure) compared with groups receiving telmisartan alone or ramipril alone.

Source: FDA drug label (Telmisartan), Alembic Pharmaceuticals Limited, effective May 29, 2026 (SPL set 4be6575f-ea8d-4cd8-a49d-3d1c93f2621a), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

17Ramipril generic labelers
28Telmisartan generic labelers
RamiprilTelmisartan
Labeled forHigh blood pressure, Heart attack and coronary artery diseaseHigh blood pressure, Heart attack and coronary artery disease
Boxed warningYesYes
Pharmacy cost (NADAC)$0.0707 per capsule 10 mg capsule$0.106 per tablet 20 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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