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What the FDA labels say about taking them together

Digoxin and ramipril

Neither FDA label names the other in its interaction, contraindication or warning sections. A label lists the interactions its studies and reports found; it is not a complete list, so ask a pharmacist before combining medicines. Labels read October 8, 2026.

Check it at the source: the digoxin FDA label on DailyMed (effective December 5, 2024, Advanz Pharma (US) Corp.); the ramipril FDA label on DailyMed (effective August 24, 2026, Lupin Pharmaceuticals, Inc.).

What does the digoxin label say about ramipril?

Digoxin's label (effective December 5, 2024) and its 2 other brand-application labels do not name ramipril in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (LANOXIN), Advanz Pharma (US) Corp., effective December 5, 2024 (SPL set d91e3646-4c63-4512-ab22-db39c085c4dc), via openFDA; the full label on DailyMed

What does the ramipril label say about digoxin?

Ramipril's label (effective August 24, 2026) does not name digoxin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Ramipril), Lupin Pharmaceuticals, Inc., effective August 24, 2026 (SPL set a8cdec12-81d1-4ef4-82c0-d05d93c37a07), via openFDA; the full label on DailyMed

A pharmacist or prescriber can say whether these two medicines suit one person together; PlainMeds does not grade interactions.

Both medicines on the record

26Digoxin generic labelers
17Ramipril generic labelers
DigoxinRamipril
Labeled forHeart failure, Atrial fibrillationHigh blood pressure, Heart attack and coronary artery disease
Boxed warningNoYes
Pharmacy cost (NADAC)$0.133 per tablet 125 mcg tablet$0.0707 per capsule 10 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

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