Lovastatin and Propranolol Interaction
Drug interaction information between Lovastatin and Propranolol.
Lovastatin and Propranolol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Lovastatin and Propranolol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These drugs do not change how the body breaks them down or how they work in the system.
FDA Label Information
Propranolol In normal volunteers, there was no clinically significant pharmacokinetic or pharmacodynamic interaction with concomitant administration of single doses of lovastatin and propranolol.
Lovastatin Also Interacts With
- Darunavir major
- Nirmatrelvir/Ritonavir major
- Spironolactone moderate
- Ketoconazole moderate
- Verapamil moderate
Frequently Asked Questions
What SPL severity band is on file for Lovastatin + Propranolol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Propranolol has 44 labeled pairs on file vs Lovastatin's 30. In the minor band specifically: Lovastatin has 11 (also Glipizide, Warfarin, Testosterone, Digoxin); Propranolol has 44 (also Clonidine, Diltiazem, Warfarin, Verapamil).
What mechanism field is on file for Lovastatin and Propranolol?
These drugs do not change how the body breaks them down or how they work in the system.
Lovastatin carries more major-labeled pairs than Propranolol
SPL source-record counts only. This page's band is minor · classes on file: Lovastatin (HMG-CoA Reductase Inhibitor (Statin)); Propranolol (Non-Selective Beta-Blocker).
Lovastatin has 2 major-labeled pairs vs Propranolol's 0. This page itself is in the minor band, not the major band.
2 major · 17 moderate · 11 minor · 30 total
- Other minor peers for Lovastatin
- Glipizide
- Warfarin
- Testosterone
- Digoxin
0 major · 0 moderate · 44 minor · 44 total
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.