lovastatin vs propranolol
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Side-by-side comparison of lovastatin and propranolol. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Propranolol In normal volunteers, there was no clinically significant pharmacokinetic or pharmacodynamic interaction with concomitant administration of single doses of lovastatin and propranolol.
Mevacor, Altoprev
Inderal
Lovastatin is a medicine that helps lower cholesterol levels in your blood. It belongs to a class of drugs called statins.
Propranolol is a medicine that can help with high blood pressure, chest pain, and other conditions. It works by blocking the effects of certain natural chemicals in your body, like adrenaline, that affect the heart and blood vessels.
Lovastatin is used to lower cholesterol and reduce the risk of heart problems. It can help prevent heart attacks, unstable angina (chest pain), and the need for procedures to open blocked arteries. It's also used to slow down the hardening of arteries in people who already have heart disease. Lovastatin can also be used in children 10-17 years of age with high cholesterol due to genetic causes.
Propranolol tablets can treat high blood pressure. It can be used alone or with other medicines. Propranolol can also help with chest pain (angina), control fast heart rate with atrial fibrillation, improve survival after a heart attack, prevent migraine headaches, and reduce tremors. It can also help with symptoms of some tumors.
Lovastatin works by blocking a substance your body needs to make cholesterol. This helps to lower the amount of cholesterol in your blood. Lowering cholesterol helps to prevent heart disease and stroke.
Propranolol is a beta-blocker. It works by blocking the effects of adrenaline on your heart and blood vessels. This helps to slow down your heart rate and lower your blood pressure.
- • Abdominal pain
- • Constipation
- • Diarrhea
- • Gas
- • Nausea
- • Tiredness
- • Dizziness
- • Nausea
- • Vomiting
- • Diarrhea
- Fatigue 1,518
- Nausea 1,396
- Diarrhoea 1,251
- Dyspnoea 1,209
- Dizziness 1,147
- Nausea 4,279
- Headache 3,785
- Fatigue 3,752
- Diarrhoea 3,119
- Dizziness 3,102
Lovastatin can cause muscle problems, including muscle breakdown (rhabdomyolysis), which can lead to kidney damage. The risk is higher if you take certain other medicines with lovastatin. You should not take lovastatin if you have liver problems or are pregnant or breastfeeding.
Propranolol is contraindicated in people with cardiogenic shock, very slow heart rate, asthma, or those who are allergic to it.
You should not take lovastatin if you are pregnant or breastfeeding. It can harm your unborn baby. If you are a woman who could become pregnant, use effective birth control while taking lovastatin.
Tell your doctor if you are pregnant or plan to become pregnant. Propranolol may affect your baby. Talk to your doctor about the risks and benefits of taking propranolol during pregnancy or while breastfeeding.
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How to Read This lovastatin vs propranolol Comparison
lovastatin is classified in the HMG-CoA Reductase Inhibitor (Statin) drug class, while propranolol sits within the Non-Selective Beta-Blocker class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, lovastatin has 6,521 submissions while propranolol has 18,037. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to these drugs do not change how the body breaks them down or how they work in the system.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for lovastatin or propranolol.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.