Lovastatin and Glipizide Interaction
Drug interaction information between Lovastatin and Glipizide.
Lovastatin and Glipizide have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Lovastatin and Glipizide. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Studies show these drugs do not interfere with each other when taken at the same time.
FDA Label Information
Oral Hypoglycemic Agents In pharmacokinetic studies of lovastatin in hypercholesterolemic non-insulin dependent diabetic patients, there was no drug interaction with glipizide or with chlorpropamide (see CLINICAL PHARMACOLOGY , Clinical Studies in Adults ).
Lovastatin Also Interacts With
- Darunavir major
- Nirmatrelvir/Ritonavir major
- Spironolactone moderate
- Ketoconazole moderate
- Verapamil moderate
Glipizide Also Interacts With
- Fluconazole minor
- Colesevelam minor
- Probenecid minor
- Phenytoin minor
- Posaconazole minor
Frequently Asked Questions
What SPL severity band is on file for Lovastatin + Glipizide?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Lovastatin has 30 labeled pairs on file vs Glipizide's 8. In the minor band specifically: Lovastatin has 11 (also Propranolol, Warfarin, Testosterone, Digoxin); Glipizide has 8 (also Fluconazole, Colesevelam, Probenecid, Phenytoin).
What mechanism field is on file for Lovastatin and Glipizide?
Studies show these drugs do not interfere with each other when taken at the same time.
Lovastatin carries more major-labeled pairs than Glipizide
SPL source-record counts only. This page's band is minor · classes on file: Lovastatin (HMG-CoA Reductase Inhibitor (Statin)); Glipizide (Sulfonylurea).
Lovastatin has 2 major-labeled pairs vs Glipizide's 0. This page itself is in the minor band, not the major band.
2 major · 17 moderate · 11 minor · 30 total
- Other minor peers for Lovastatin
- Propranolol
- Warfarin
- Testosterone
- Digoxin
0 major · 0 moderate · 8 minor · 8 total
- Other minor peers for Glipizide
- Fluconazole
- Colesevelam
- Probenecid
- Phenytoin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.