Thioridazine and Carbamazepine Interaction
Drug interaction information between Thioridazine and Carbamazepine.
Thioridazine and Carbamazepine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Thioridazine and Carbamazepine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
When these liquid drugs are mixed, they form a solid clump that may be seen in the stool.
FDA Label Information
Subsequent testing has shown that mixing carbamazepine suspension and chlorpromazine solution (both generic and brand name) as well as carbamazepine suspension and liquid Mellaril, resulted in the occurrence of this precipitate.
Thioridazine Also Interacts With
- Fluoxetine major
- Paroxetine major
- Rolapitant major
- Abiraterone moderate
- Darifenacin moderate
Carbamazepine Also Interacts With
- Nirmatrelvir/Ritonavir major
- Ranolazine major
- Risperidone major
- Lithium moderate
- Apixaban moderate
Frequently Asked Questions
What SPL severity band is on file for Thioridazine + Carbamazepine?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Carbamazepine has 129 labeled pairs on file vs Thioridazine's 17. In the minor band specifically: Thioridazine has 11 (also Propranolol, Pindolol, Bupropion, Clozapine); Carbamazepine has 110 (also Omeprazole, Ibuprofen, Citalopram, Amitriptyline).
What mechanism field is on file for Thioridazine and Carbamazepine?
When these liquid drugs are mixed, they form a solid clump that may be seen in the stool.
Carbamazepine's labeled portfolio outnumbers Thioridazine
SPL source-record counts only. This page's band is minor · classes on file: Thioridazine (Typical Antipsychotic (Phenothiazine)); Carbamazepine (Anticonvulsant).
3 major · 3 moderate · 11 minor · 17 total
- Other minor peers for Thioridazine
- Propranolol
- Pindolol
- Bupropion
- Clozapine
3 major · 16 moderate · 110 minor · 129 total
- Other minor peers for Carbamazepine
- Omeprazole
- Ibuprofen
- Citalopram
- Amitriptyline
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.