Skip to main content

What the FDA labels say about taking them together

Pindolol and thioridazine

Thioridazine's FDA label of November 11, 2025 names pindolol in its contraindications section; the pindolol label PlainMeds reads does not name thioridazine. The thioridazine label: “Reduced cytochrome P450 2D6 isozyme activity drugs that inhibit this isozyme and certain other drugs appear to appreciably inhibit the metabolism of thioridazine.”

Check it at the source: the pindolol FDA label on DailyMed (effective March 17, 2026, Sun Pharmaceutical Industries, Inc.); the thioridazine FDA label on DailyMed (effective November 11, 2025, Mylan Institutional Inc.).

What does the pindolol label say about thioridazine?

Pindolol's label (effective March 17, 2026) does not name thioridazine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Pindolol), Sun Pharmaceutical Industries, Inc., effective March 17, 2026 (SPL set b331a73f-bf7b-4442-8901-36d016530279), via openFDA; the full label on DailyMed

What does the thioridazine label say about pindolol?

Thioridazine label, contraindications

Reduced cytochrome P450 2D6 isozyme activity drugs that inhibit this isozyme (e.g., fluoxetine and paroxetine) and certain other drugs (e.g., fluvoxamine, propranolol, and pindolol) appear to appreciably inhibit the metabolism of thioridazine.

Source: FDA drug label (Thioridazine Hydrochloride), Mylan Institutional Inc., effective November 11, 2025 (SPL set 52fea941-0b47-41c1-b00d-f88150e8ab93), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

8Pindolol generic labelers
5Thioridazine generic labelers
PindololThioridazine
Labeled forHigh blood pressuren/a
Boxed warningNoYes
Pharmacy cost (NADAC)$0.854 per tablet 10 mg tablet$0.571 per tablet 25 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?