Sulfasalazine and Prenatal Multivitamin Interaction
Drug interaction information between Sulfasalazine and Prenatal Multivitamin.
Sulfasalazine and Prenatal Multivitamin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Sulfasalazine and Prenatal Multivitamin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
This drug stops your body from properly absorbing and using folic acid. This can lead to a shortage of this vitamin in your system.
FDA Label Information
• Sulfasalazine: Inhibits the absorption and metabolism of folic acid.
Sulfasalazine Also Interacts With
- Lidocaine Topical moderate
- Sofosbuvir/Velpatasvir moderate
- Digoxin minor
- Drospirenone/Ethinyl Estradiol minor
- Etanercept minor
Prenatal Multivitamin Also Interacts With
- Trimethoprim moderate
- Phenytoin moderate
- Metformin minor
- Fluoxetine minor
- Ibuprofen minor
Frequently Asked Questions
What SPL severity band is on file for Sulfasalazine + Prenatal Multivitamin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Prenatal Multivitamin has 23 labeled pairs on file vs Sulfasalazine's 7. In the minor band specifically: Sulfasalazine has 5 (also Digoxin, Drospirenone, Etanercept, Methylprednisolone); Prenatal Multivitamin has 21 (also Metformin, Fluoxetine, Ibuprofen, Potassium Chloride).
What mechanism field is on file for Sulfasalazine and Prenatal Multivitamin?
This drug stops your body from properly absorbing and using folic acid. This can lead to a shortage of this vitamin in your system.
Prenatal Multivitamin's labeled portfolio outnumbers Sulfasalazine
SPL source-record counts only. This page's band is minor · classes on file: Sulfasalazine (Disease-Modifying Antirheumatic Drug (DMARD)); Prenatal Multivitamin (Prenatal Vitamin).
0 major · 2 moderate · 5 minor · 7 total
- Other minor peers for Sulfasalazine
- Digoxin
- Drospirenone
- Etanercept
- Methylprednisolone
0 major · 2 moderate · 21 minor · 23 total
- Other minor peers for Prenatal Multivitamin
- Metformin
- Fluoxetine
- Ibuprofen
- Potassium Chloride
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.