Prenatal Multivitamin and Ibuprofen Interaction

Drug interaction information between Prenatal Multivitamin and Ibuprofen.

Prenatal Multivitamin and Ibuprofen have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Prenatal Multivitamin and Ibuprofen. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Prenatal Multivitamin

Prenatal Vitamin

Drug B

Ibuprofen

Nonsteroidal Anti-Inflammatory Drug (NSAID)

How They Interact

Ibuprofen is a type of NSAID that can interfere with how your body absorbs or uses certain vitamins in your prenatal supplement.

FDA Label Information

• NSAIDs include ibuprofen, naproxen, indomethacin and sulindac.

Frequently Asked Questions

What SPL severity band is on file for Prenatal Multivitamin + Ibuprofen?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Prenatal Multivitamin has 23 labeled pairs on file vs Ibuprofen's 9. In the minor band specifically: Prenatal Multivitamin has 21 (also Metformin, Fluoxetine, Potassium Chloride, Lamotrigine); Ibuprofen has 7 (also Carbamazepine, Digoxin, Fluconazole, Terazosin).

What mechanism field is on file for Prenatal Multivitamin and Ibuprofen?

Ibuprofen is a type of NSAID that can interfere with how your body absorbs or uses certain vitamins in your prenatal supplement.

Prenatal Multivitamin's labeled portfolio outnumbers Ibuprofen

SPL source-record counts only. This page's band is minor · classes on file: Prenatal Multivitamin (Prenatal Vitamin); Ibuprofen (Nonsteroidal Anti-Inflammatory Drug (NSAID)).

Prenatal Multivitamin

0 major · 2 moderate · 21 minor · 23 total

Ibuprofen

0 major · 2 moderate · 7 minor · 9 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.