Itraconazole and Tamsulosin Interaction
Drug interaction information between Itraconazole and Tamsulosin.
Itraconazole and Tamsulosin have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Itraconazole and Tamsulosin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Itraconazole stops your body from breaking down tamsulosin normally, which can lead to too much medicine in your system.
Itraconazole Also Interacts With
- Isavuconazonium major
- Lurasidone major
- Pimozide major
- Methadone major
- Midazolam major
Tamsulosin Also Interacts With
- Furosemide major
- Paroxetine moderate
- Warfarin moderate
- Erythromycin moderate
- Terbinafine moderate
Frequently Asked Questions
What SPL severity band is on file for Itraconazole + Tamsulosin?
Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Itraconazole has 116 labeled pairs on file vs Tamsulosin's 18. In the moderate band specifically: Itraconazole has 20 (also Rivaroxaban, Tenofovir Disoproxil, Glecaprevir/Pibrentasvir, Aliskiren); Tamsulosin has 8 (also Paroxetine, Warfarin, Erythromycin, Terbinafine).
What mechanism field is on file for Itraconazole and Tamsulosin?
Itraconazole stops your body from breaking down tamsulosin normally, which can lead to too much medicine in your system.
Itraconazole carries more major-labeled pairs than Tamsulosin
SPL source-record counts only. This page's band is moderate · classes on file: Itraconazole (Azole Antifungal); Tamsulosin (Alpha-1 Adrenergic Blocker).
Itraconazole has 19 major-labeled pairs vs Tamsulosin's 1. This page itself is in the moderate band, not the major band.
19 major · 20 moderate · 77 minor · 116 total
- Other moderate peers for Itraconazole
- Rivaroxaban
- Tenofovir Disoproxil
- Glecaprevir/Pibrentasvir
- Aliskiren
1 major · 8 moderate · 9 minor · 18 total
- Other moderate peers for Tamsulosin
- Paroxetine
- Warfarin
- Erythromycin
- Terbinafine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.