Skip to main content

What the FDA labels say about taking them together

Tamsulosin and warfarin

Tamsulosin's FDA label of December 1, 2025 names warfarin in its drug interactions section; the warfarin label PlainMeds reads does not name tamsulosin.

Check it at the source: the tamsulosin FDA label on DailyMed (effective December 1, 2025, Synthon Pharmaceuticals, Inc.); the warfarin FDA label on DailyMed (effective May 29, 2026, Amneal Pharmaceuticals LLC).

What does the tamsulosin label say about warfarin?

Tamsulosin label, drug interactions

Caution should be exercised with concomitant administration of warfarin and tamsulosin hydrochloride capsules [see Warnings and Precautions (5.2) and Clinical Pharmacology (12.3) ].

Tamsulosin label, warnings and precautions

Use with caution in combination with moderate inhibitors of CYP3A4, with strong or moderate inhibitors of CYP2D6, in patients known to be CYP2D6 poor metabolizers, or in combination with other cytochrome P450 inhibitors. ( 5.2 , 7.1 , 12.3 ) Should not be used in combination with other alpha adrenergic blocking agents ( 5.2 , 7.2 , 12.3 ) Exercise caution with concomitant administration of warfarin ( 5.2 , 7.4 , 12.3 ) Advise patients about the possibility and seriousness of priapism ( 5.3 ) Intraoperative Floppy Iris Syndrome has been observed during cataract and glaucoma surgery in some patients.

Source: FDA drug label (Tamsulosin hydrochloride), Synthon Pharmaceuticals, Inc., effective December 1, 2025 (SPL set 13a5032d-0be1-4001-916e-459f0b1a051d), via openFDA; the full label on DailyMed

What does the warfarin label say about tamsulosin?

Warfarin's label (effective May 29, 2026) does not name tamsulosin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Warfarin Sodium), Amneal Pharmaceuticals LLC, effective May 29, 2026 (SPL set 558b7a0d-5490-4c1b-802e-3ab3f1efe760), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

38Tamsulosin generic labelers
19Warfarin generic labelers
TamsulosinWarfarin
Labeled forEnlarged prostate (BPH)Blood clots (DVT and PE), Atrial fibrillation
Boxed warningNoYes
Pharmacy cost (NADAC)$0.05 per capsule 0.4 mg capsule$0.093 per tablet 2 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?