itraconazole vs tamsulosin

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Side-by-side comparison of itraconazole and tamsulosin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

moderate Known Drug Interaction

Table 1:Drug Interactions with Itraconazole that Affect Concomitant Drug Concentrations Examples of Concomitant Drugs Within Class Prevention or Management Drug Interactions with Itraconazole that Increase Concomitant Drug Concentrations and May Increase Risk of Adverse Reactions Associated with the Concomitant Drug Alpha Blockers Alfuzosin Silodosin Tamsulosin Not recommended during and 2 weeks after itraconazole treatment.

Drug Class
itraconazole Azole Antifungal
tamsulosin Alpha-1 Adrenergic Blocker
Type
itraconazole Prescription
tamsulosin Prescription
Summary
itraconazole

Itraconazole capsules are an antifungal medicine. They treat fungal infections in your body.

tamsulosin

Tamsulosin (Flomax) helps to improve urination in men with enlarged prostate glands. It relaxes the muscles in the prostate and bladder, making it easier to urinate.

What It Treats
itraconazole

Itraconazole treats fungal infections like blastomycosis, histoplasmosis, and aspergillosis. It can help both people with healthy immune systems and those with weakened immune systems. It also treats onychomycosis, a fungal infection of the toenails or fingernails.

tamsulosin

This medicine treats the symptoms of an enlarged prostate, also known as benign prostatic hyperplasia (BPH). BPH can cause problems with urination, like difficulty starting or stopping the flow of urine. Tamsulosin helps to relieve these symptoms.

How It Works
itraconazole

Itraconazole stops fungi from growing. It does this by interfering with the production of a substance fungi need to build their cell membranes. This eventually kills the fungus and clears the infection.

tamsulosin

Tamsulosin blocks alpha-1 adrenoceptors in the prostate and bladder. These receptors control muscle tightness. By blocking them, tamsulosin relaxes the muscles, which improves urine flow.

Common Side Effects
itraconazole
  • Nausea
  • Rash
  • Headache
tamsulosin
  • Headache
  • Dizziness
  • Runny nose
  • Infection
  • Abnormal ejaculation
FAERS Reports
itraconazole
  • Drug Interaction 1,118
  • Pyrexia 568
  • Dyspnoea 474
  • Pneumonia 461
  • Nausea 445
tamsulosin
  • Fatigue 1,417
  • Dyspnoea 1,332
  • Dizziness 1,131
  • Diarrhoea 1,121
  • Headache 883
Serious Warnings
itraconazole

Itraconazole can cause congestive heart failure. You should not take this medicine if you have heart problems. Itraconazole can also interact with many other medicines. Some of these interactions can be dangerous or even fatal. Check with your doctor about all the medicines you take.

tamsulosin

Tamsulosin can cause a sudden drop in blood pressure when you stand up, leading to dizziness or fainting. Avoid situations where you could get hurt if you faint. Tell your eye doctor if you are planning to have cataract or glaucoma surgery, as tamsulosin can cause complications during the procedure. You should be screened for prostate cancer before starting tamsulosin and regularly after.

Pregnancy
itraconazole

You should not take itraconazole if you are pregnant or plan to become pregnant. It can harm your unborn baby. Talk to your doctor about safe alternatives.

tamsulosin

This medicine is only for men. It is not meant to be used by women. There is no information about the safety of tamsulosin during pregnancy or breastfeeding because it is not used in women.

Also Compare, Nearby Drugs

How to Read This itraconazole vs tamsulosin Comparison

itraconazole is classified in the Azole Antifungal drug class, while tamsulosin sits within the Alpha-1 Adrenergic Blocker class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, itraconazole has 3,066 submissions while tamsulosin has 5,884. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to itraconazole stops your body from breaking down tamsulosin normally, which can lead to too much medicine in your system.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for itraconazole or tamsulosin.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.