Gentamicin and Perindopril Interaction

Drug interaction information between Gentamicin and Perindopril.

Gentamicin and Perindopril have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Gentamicin and Perindopril. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Gentamicin

Aminoglycoside Antibiotic

Drug B

Perindopril

ACE Inhibitor

How They Interact

Research in animals suggests these two drugs might interact, although the exact way they affect humans is not yet fully understood.

FDA Label Information

7.6 Gentamicin Animal data have suggested the possibility of interaction between perindopril and gentamicin.

Frequently Asked Questions

What SPL severity band is on file for Gentamicin + Perindopril?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Perindopril has 9 labeled pairs on file vs Gentamicin's 7. In the minor band specifically: Gentamicin has 6 (also Bictegravir, Digoxin, Emtricitabine/Tenofovir, Piperacillin/Tazobactam); Perindopril has 3 (also Lithium, Digoxin).

What mechanism field is on file for Gentamicin and Perindopril?

Research in animals suggests these two drugs might interact, although the exact way they affect humans is not yet fully understood.

Perindopril's labeled portfolio outnumbers Gentamicin

SPL source-record counts only. This page's band is minor · classes on file: Gentamicin (Aminoglycoside Antibiotic); Perindopril (ACE Inhibitor).

Gentamicin

1 major · 0 moderate · 6 minor · 7 total

Perindopril

1 major · 5 moderate · 3 minor · 9 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.