Budesonide and Itraconazole Interaction
Drug interaction information between Budesonide and Itraconazole.
Budesonide and Itraconazole have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Budesonide and Itraconazole. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Itraconazole can slow down the way your body breaks down this steroid, which may cause the steroid to stay in your system longer than usual.
FDA Label Information
Budesonide (inhalation) a Budesonide (non-inhalation) Ciclesonide (inhalation) Cyclosporine (IV) a Cyclosporine (non-IV) Dexamethasone a Fluticasone (inhalation) a Fluticasone (nasal)Methylprednisolone a Tacrolimus (IV) a Tacrolimus (oral) Monitor for adverse reactions.
Budesonide Also Interacts With
- Darunavir moderate
- Nirmatrelvir/Ritonavir moderate
- Budesonide/Formoterol minor
Itraconazole Also Interacts With
- Isavuconazonium major
- Lurasidone major
- Pimozide major
- Methadone major
- Midazolam major
Frequently Asked Questions
What SPL severity band is on file for Budesonide + Itraconazole?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Itraconazole has 116 labeled pairs on file vs Budesonide's 4. In the minor band specifically: Budesonide has 2 (also Budesonide/Formoterol); Itraconazole has 77 (also Fluticasone, Meloxicam, Buspirone, Oxycodone).
What mechanism field is on file for Budesonide and Itraconazole?
Itraconazole can slow down the way your body breaks down this steroid, which may cause the steroid to stay in your system longer than usual.
Itraconazole carries more major-labeled pairs than Budesonide
SPL source-record counts only. This page's band is minor · classes on file: Budesonide (Corticosteroid); Itraconazole (Azole Antifungal).
Itraconazole has 19 major-labeled pairs vs Budesonide's 0. This page itself is in the minor band, not the major band.
0 major · 2 moderate · 2 minor · 4 total
- Other minor peers for Budesonide
- Budesonide/Formoterol
19 major · 20 moderate · 77 minor · 116 total
- Other minor peers for Itraconazole
- Fluticasone
- Meloxicam
- Buspirone
- Oxycodone
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.