budesonide vs itraconazole

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Side-by-side comparison of budesonide and itraconazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Budesonide (inhalation) a Budesonide (non­-­­­inhalation) Ciclesonide (inhalation) Cyclosporine (IV) a Cyclosporine (non-IV) Dexamethasone a Fluticasone (inhalation) a Fluticasone (nasal)Methylprednisolone a Tacrolimus (IV) a Tacrolimus (oral) Monitor for adverse reactions.

Drug Class
budesonide Corticosteroid
itraconazole Azole Antifungal
Type
budesonide Prescription
itraconazole Prescription
Summary
budesonide

Budesonide nasal spray is a steroid medicine. It helps to relieve allergy symptoms like sneezing and runny nose.

itraconazole

Itraconazole capsules are an antifungal medicine. They treat fungal infections in your body.

What It Treats
budesonide

This medicine temporarily relieves allergy symptoms. It can help with nasal congestion, runny nose, itchy nose, and sneezing. These symptoms may be caused by hay fever or other upper respiratory allergies.

itraconazole

Itraconazole treats fungal infections like blastomycosis, histoplasmosis, and aspergillosis. It can help both people with healthy immune systems and those with weakened immune systems. It also treats onychomycosis, a fungal infection of the toenails or fingernails.

How It Works
budesonide

Budesonide is a corticosteroid. It reduces inflammation in the nasal passages. This helps to relieve allergy symptoms.

itraconazole

Itraconazole stops fungi from growing. It does this by interfering with the production of a substance fungi need to build their cell membranes. This eventually kills the fungus and clears the infection.

Common Side Effects
budesonide
  • Headache
  • Cough
itraconazole
  • Nausea
  • Rash
  • Headache
FAERS Reports
budesonide
  • Dyspnoea 6,364
  • Asthma 4,695
  • Fatigue 3,354
  • Cough 3,164
  • Headache 2,978
itraconazole
  • Drug Interaction 1,118
  • Pyrexia 568
  • Dyspnoea 474
  • Pneumonia 461
  • Nausea 445
Serious Warnings
budesonide

The growth rate of some children may be slower while using this product. Talk to your child’s doctor if your child needs to use the spray for longer than two months a year. Do not spray into eyes or mouth. If allergy symptoms do not improve after two weeks, stop using and talk to a doctor.

itraconazole

Itraconazole can cause congestive heart failure. You should not take this medicine if you have heart problems. Itraconazole can also interact with many other medicines. Some of these interactions can be dangerous or even fatal. Check with your doctor about all the medicines you take.

Pregnancy
budesonide

Tell your doctor if you are pregnant or plan to become pregnant. Talk to your doctor about the risks and benefits of using budesonide nasal spray during pregnancy. It is not known if budesonide passes into breast milk.

itraconazole

You should not take itraconazole if you are pregnant or plan to become pregnant. It can harm your unborn baby. Talk to your doctor about safe alternatives.

Also Compare, Nearby Drugs

How to Read This budesonide vs itraconazole Comparison

budesonide is classified in the Corticosteroid drug class, while itraconazole sits within the Azole Antifungal class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, budesonide has 20,555 submissions while itraconazole has 3,066. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to itraconazole can slow down the way your body breaks down this steroid, which may cause the steroid to stay in your system longer than usual.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for budesonide or itraconazole.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.