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What the FDA labels say about taking them together

Itraconazole and meloxicam

Itraconazole's FDA label of July 13, 2026 names meloxicam in its drug interactions section; the meloxicam labels PlainMeds reads (4) do not name itraconazole. The itraconazole label: “Nonsteroidal Anti-Inflammatory Drugs Meloxicam Concomitant drug dose increase may be necessary.”

Check it at the source: the itraconazole FDA label on DailyMed (effective July 13, 2026, Janssen Pharmaceuticals, Inc.); the meloxicam FDA label on DailyMed (effective January 29, 2026, PD-Rx Pharmaceuticals, Inc.).

What does the itraconazole label say about meloxicam?

Itraconazole label, drug interactions

Nonsteroidal Anti-Inflammatory Drugs Meloxicam Concomitant drug dose increase may be necessary.

Source: FDA drug label (SPORANOX), Janssen Pharmaceuticals, Inc., effective July 13, 2026 (SPL set a4d555fa-787c-40fb-bb7d-b0d4f7318fd0), via openFDA; the full label on DailyMed

What does the meloxicam label say about itraconazole?

Meloxicam's label (effective January 29, 2026) and its 3 other brand-application labels do not name itraconazole in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (MELOXICAM), PD-Rx Pharmaceuticals, Inc., effective January 29, 2026 (SPL set 19c13159-71f1-2427-e063-6394a90ad44e), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

11Itraconazole generic labelers
43Meloxicam generic labelers
ItraconazoleMeloxicam
Labeled forFungal infectionsOsteoarthritis, Rheumatoid arthritis, Pain
Boxed warningYesYes
Pharmacy cost (NADAC)$0.910 per capsule 100 mg capsule$0.0166 per tablet 7.5 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?