Bromocriptine and Pimozide Interaction
Drug interaction information between Bromocriptine and Pimozide.
Bromocriptine and Pimozide have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Bromocriptine and Pimozide. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Pimozide works against bromocriptine in the body. This makes the bromocriptine less effective at treating your condition.
FDA Label Information
Compounds in these categories result in a decreased efficacy of bromocriptine mesylate: phenothiazines, haloperidol, metoclopramide, and pimozide.
Bromocriptine Also Interacts With
- Clarithromycin moderate
- Erythromycin minor
- Haloperidol minor
- Dopamine minor
- Metoclopramide minor
Pimozide Also Interacts With
- Aprepitant major
- Citalopram major
- Clarithromycin major
- Darunavir major
- Escitalopram major
Frequently Asked Questions
What SPL severity band is on file for Bromocriptine + Pimozide?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Pimozide has 24 labeled pairs on file vs Bromocriptine's 7. In the minor band specifically: Bromocriptine has 6 (also Erythromycin, Haloperidol, Dopamine, Metoclopramide); Pimozide has 12 (also Moxifloxacin, Ziprasidone, Chlorpromazine, Thioridazine).
What mechanism field is on file for Bromocriptine and Pimozide?
Pimozide works against bromocriptine in the body. This makes the bromocriptine less effective at treating your condition.
Pimozide carries more major-labeled pairs than Bromocriptine
SPL source-record counts only. This page's band is minor · classes on file: Bromocriptine (Dopamine Agonist (Diabetes)); Pimozide (Typical Antipsychotic).
Pimozide has 12 major-labeled pairs vs Bromocriptine's 0. This page itself is in the minor band, not the major band.
0 major · 1 moderate · 6 minor · 7 total
- Other minor peers for Bromocriptine
- Erythromycin
- Haloperidol
- Dopamine
- Metoclopramide
12 major · 0 moderate · 12 minor · 24 total
- Other minor peers for Pimozide
- Moxifloxacin
- Ziprasidone
- Chlorpromazine
- Thioridazine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.