Skip to main content

What the FDA labels say about taking them together

Moxifloxacin and pimozide

Pimozide's FDA label of August 12, 2026 names moxifloxacin in its drug interactions section; the moxifloxacin labels PlainMeds reads (3) do not name pimozide. The pimozide label: “… mesoridazine, thioridazine, chlorpromazine, droperidol, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate, probucol, tacrolimus …”

Check it at the source: the moxifloxacin FDA label on DailyMed (effective March 17, 2026, Macleods Pharmaceuticals Limited); the pimozide FDA label on DailyMed (effective August 12, 2026, Par Health USA, LLC).

What does the moxifloxacin label say about pimozide?

Moxifloxacin's label (effective March 17, 2026) and its 2 other brand-application labels do not name pimozide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Moxifloxacin), Macleods Pharmaceuticals Limited, effective March 17, 2026 (SPL set 182ecd0f-714f-42f0-9b16-fb604cf15786), via openFDA; the full label on DailyMed

What does the pimozide label say about moxifloxacin?

Pimozide label, drug interactions

Accordingly, pimozide should not be given with dofetilide, sotalol, quinidine, other Class Ia and III anti-arrhythmics, mesoridazine, thioridazine, chlorpromazine, droperidol, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate, probucol, tacrolimus, ziprasidone, or other drugs that have demonstrated QT prolongation as one of their pharmacodynamic effects.

Source: FDA drug label (Pimozide), Par Health USA, LLC, effective August 12, 2026 (SPL set 70b079e2-a1f7-4a93-8685-d60a4d7c1280), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

32Moxifloxacin generic labelers
2Pimozide generic labelers
MoxifloxacinPimozide
Labeled forBacterial infectionsn/a
Boxed warningYesNo
Pharmacy cost (NADAC)$1.60 per mL 0.5% eye drops$1.23 per tablet 1 mg tablet
Shortage nowA presentation being discontinuedNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?