Bromocriptine and Clarithromycin Interaction
Drug interaction information between Bromocriptine and Clarithromycin.
Bromocriptine and Clarithromycin have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Bromocriptine and Clarithromycin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Clarithromycin slows down the liver enzyme that breaks down bromocriptine, which can cause the drug to build up in your system.
FDA Label Information
Other Drugs Metabolized by CYP3A: Alfentanil Bromocriptine Cilostazol Methylprednisolone Vinblastine Phenobarbital St. John’s Wort Use With Caution There have been spontaneous or published reports of CYP3A based interactions of clarithromycin with alfentanil, methylprednisolone, cilostazol, bromocriptine, vinblastine, phenobarbital, and St.
Bromocriptine Also Interacts With
- Erythromycin minor
- Pimozide minor
- Haloperidol minor
- Dopamine minor
- Metoclopramide minor
Clarithromycin Also Interacts With
- Quetiapine major
- Pioglitazone major
- Fluconazole major
- Cyclosporine major
- Lurasidone major
Frequently Asked Questions
What SPL severity band is on file for Bromocriptine + Clarithromycin?
Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Clarithromycin has 81 labeled pairs on file vs Bromocriptine's 7. In the moderate band specifically: Bromocriptine has 1; Clarithromycin has 35 (also Omeprazole, Methylprednisolone, Sildenafil, Valproate).
What mechanism field is on file for Bromocriptine and Clarithromycin?
Clarithromycin slows down the liver enzyme that breaks down bromocriptine, which can cause the drug to build up in your system.
Clarithromycin carries more major-labeled pairs than Bromocriptine
SPL source-record counts only. This page's band is moderate · classes on file: Bromocriptine (Dopamine Agonist (Diabetes)); Clarithromycin (Macrolide Antibiotic).
Clarithromycin has 16 major-labeled pairs vs Bromocriptine's 0. This page itself is in the moderate band, not the major band.
0 major · 1 moderate · 6 minor · 7 total
Bromocriptine has no other moderate-band peer in this dataset besides Clarithromycin.
16 major · 35 moderate · 30 minor · 81 total
- Other moderate peers for Clarithromycin
- Omeprazole
- Methylprednisolone
- Sildenafil
- Valproate
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.