What the FDA labels say about taking them together
Citalopram and pimozide
Citalopram's FDA label of October 9, 2023 names pimozide in its contraindications section, and pimozide's label names citalopram too. The citalopram label: “Concomitant use of citalopram with pimozide increases plasma concentrations of pimozide, a drug with a narrow therapeutic index, and may increase the risk of QT prolongation and/or ventricular arrhythmias compared to …”
Check it at the source: the citalopram FDA label on DailyMed (effective October 9, 2023, Allergan, Inc.); the pimozide FDA label on DailyMed (effective August 12, 2026, Par Health USA, LLC).
What does the citalopram label say about pimozide?
Citalopram label, contraindicationsCONTRAINDICATIONS CELEXA is contraindicated in patients: taking, or within 14 days of stopping, MAOIs (including MAOIs such as linezolid or intravenous methylene blue) because of an increased risk of serotonin syndrome [see Warnings and Precautions ( 5.3 ), Drug Interactions ( 7 )]. taking pimozide because of risk of QT prolongation [ see Drug Interactions ( 7 )]. with known hypersensitivity to citalopram or any of the inactive ingredients in CELEXA.
Citalopram label, drug interactionsPimozide Clinical Impact: Concomitant use of CELEXA with pimozide increases plasma concentrations of pimozide, a drug with a narrow therapeutic index, and may increase the risk of QT prolongation and/or ventricular arrhythmias compared to use of CELEXA alone. Intervention: CELEXA is contraindicated in patients taking pimozide [see Contraindications (), Warnings and Precautions ()].
Source: FDA drug label (Citalopram, NDA215428), Almatica Pharma LLC, effective October 7, 2025 (SPL set 2f815b0c-6da7-cb61-e89c-7de628092d0d), via openFDA
Source: FDA drug label (Celexa), NDA020822 (Abbvie), as published by Allergan, Inc., effective October 9, 2023 (SPL set 4259d9b1-de34-43a4-85a8-41dd214e9177), via openFDA; the full label on DailyMed
What does the pimozide label say about citalopram?
Pimozide label, contraindicationsConcomitant use in patients taking Celexa or Lexapro is contraindicated (see PRECAUTIONS - DRUG INTERACTIONS - Pimozide and Celexa ).
Pimozide label, drug interactionsPimozide and Celexa: In a controlled study, a single dose of pimozide 2 mg coadministered with racemic citalopram 40 mg given once daily for 11 days was associated with a mean increase in QTc values of approximately 10 msec compared to pimozide given alone.
Source: FDA drug label (Pimozide), Par Health USA, LLC, effective August 12, 2026 (SPL set 70b079e2-a1f7-4a93-8685-d60a4d7c1280), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Citalopram | Pimozide | |
|---|---|---|
| Labeled for | Depression | n/a |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.026 per tablet 10 mg tablet | $1.23 per tablet 1 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once