What the FDA labels say about taking them together
Bromocriptine and erythromycin
Bromocriptine's FDA label (Cycloset) of January 12, 2026 names erythromycin in its drug interactions section, and erythromycin's label names bromocriptine too. The erythromycin label: “… disopyramide, rifabutin, quinidine, methylprednisolone, cilostazol, vinblastine, and bromocriptine.”
Check it at the source: the bromocriptine FDA label on DailyMed (effective July 27, 2026, ANI Pharmaceuticals, Inc.); the erythromycin FDA label on DailyMed (effective August 1, 2024, Teva Pharmaceuticals USA, Inc.).
What does the bromocriptine label say about erythromycin?
Cycloset label (Avvisto Therapeutics LLC, January 12, 2026), drug interactionsCYCLOSET dose should not exceed 1.6 mg once daily during concomitant use of a moderate CYP3A4 inhibitor (e.g., erythromycin).
Source: FDA drug label (Cycloset, NDA020866), Avvisto Therapeutics LLC, effective January 12, 2026 (SPL set e42ba916-16b9-4d1c-8d09-9d2fbb1b6c20), via openFDA
Source: FDA drug label (Bromocriptine Mesylate), ANI Pharmaceuticals, Inc., effective July 27, 2026 (SPL set 17f3a343-1782-4799-95ba-31dfe93be2cf), via openFDA; the full label on DailyMed
What does the erythromycin label say about bromocriptine?
Erythromycin label, drug interactionsThere have been spontaneous or published reports of CYP3A based interactions of erythromycin with cyclosporine, carbamazepine, tacrolimus, alfentanil, disopyramide, rifabutin, quinidine, methyl-prednisolone, cilostazol, vinblastine, and bromocriptine.
Ery-Ped label (Azurity Pharmaceuticals, Inc. (formerly Arbor Pharmaceuticals), December 16, 2023), drug interactionsReduction of sildenafil dosage should be considered. (See Viagra package insert.) There have been spontaneous or published reports of CYP3A based interactions of erythromycin with cyclosporine, carbamazepine, tacrolimus, alfentanil, disopyramide, rifabutin, quinidine, methylprednisolone, cilostazol, vinblastine, and bromocriptine.
Erythromycin label (Dr. Reddy's Labratories Inc., September 25, 2025), drug interactionsReduction of sildenafil dosage should be considered. (See Viagra package insert.) There have been spontaneous or published reports of CYP3A based interactions of erythromycin with carbamazepine, cyclosporine, tacrolimus, alfentanil, disopyramide, bromocriptine, rifabutin, quinidine methylprednisolone, cilostazol, and vinblastine.
Source: FDA drug label (Ery-Ped, NDA050207), Azurity Pharmaceuticals, Inc. (formerly Arbor Pharmaceuticals), effective December 16, 2023 (SPL set 04775721-ab87-4b66-808c-d67a21032385), via openFDA
Source: FDA drug label (Erythromycin, NDA050536), Dr. Reddy's Labratories Inc., effective September 25, 2025 (SPL set a2dcb48a-212c-1b0c-ec35-ee2ade85847f), via openFDA
Source: FDA drug label (Erythromycin), Teva Pharmaceuticals USA, Inc., effective August 1, 2024 (SPL set 75a0bd5a-d09f-483b-bfd8-f8343b149eb2), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Bromocriptine | Erythromycin | |
|---|---|---|
| Labeled for | Parkinson's disease, Type 2 diabetes | Bacterial infections, Acne |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $1.61 per tablet 2.5 mg tablet | $1.96 per tablet 250 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once