Bromocriptine and Erythromycin Interaction
Drug interaction information between Bromocriptine and Erythromycin.
Bromocriptine and Erythromycin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Bromocriptine and Erythromycin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Erythromycin slows down how fast your body gets rid of bromocriptine. This causes the medicine to build up to higher levels in your blood.
FDA Label Information
The concomitant use of macrolide antibiotics such as erythromycin was shown to increase the plasma levels of bromocriptine (mean AUC and C max values increased 3.7-fold and 4.6-fold, respectively).
Bromocriptine Also Interacts With
- Clarithromycin moderate
- Pimozide minor
- Haloperidol minor
- Dopamine minor
- Metoclopramide minor
Erythromycin Also Interacts With
- Eplerenone major
- Pitavastatin major
- Risperidone major
- Sildenafil major
- Lefamulin moderate
Frequently Asked Questions
What SPL severity band is on file for Bromocriptine + Erythromycin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Erythromycin has 63 labeled pairs on file vs Bromocriptine's 7. In the minor band specifically: Bromocriptine has 6 (also Pimozide, Haloperidol, Dopamine, Metoclopramide); Erythromycin has 53 (also Acetaminophen/Oxycodone, Alprazolam, Atorvastatin, Buprenorphine).
What mechanism field is on file for Bromocriptine and Erythromycin?
Erythromycin slows down how fast your body gets rid of bromocriptine. This causes the medicine to build up to higher levels in your blood.
Erythromycin carries more major-labeled pairs than Bromocriptine
SPL source-record counts only. This page's band is minor · classes on file: Bromocriptine (Dopamine Agonist (Diabetes)); Erythromycin (Macrolide Antibiotic).
Erythromycin has 4 major-labeled pairs vs Bromocriptine's 0. This page itself is in the minor band, not the major band.
0 major · 1 moderate · 6 minor · 7 total
- Other minor peers for Bromocriptine
- Pimozide
- Haloperidol
- Dopamine
- Metoclopramide
4 major · 6 moderate · 53 minor · 63 total
- Other minor peers for Erythromycin
- Acetaminophen/Oxycodone
- Alprazolam
- Atorvastatin
- Buprenorphine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.