Aspirin and Colestipol Interaction
Drug interaction information between Aspirin and Colestipol.
Aspirin and Colestipol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Aspirin and Colestipol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Colestipol does not seem to lower the levels of aspirin in your blood or stop it from being absorbed.
FDA Label Information
No depressant effect on blood levels in humans was noted when colestipol hydrochloride was administered with any of the following drugs: aspirin, clindamycin, clofibrate, methyldopa, nicotinic acid (niacin), tolbutamide, phenytoin or warfarin.
Aspirin Also Interacts With
- Atenolol major
- Fluoxetine major
- Ibandronate major
- Alendronate moderate
- Apixaban moderate
Colestipol Also Interacts With
- Olmesartan moderate
- Furosemide minor
- Propranolol minor
- Warfarin minor
- Clindamycin minor
Frequently Asked Questions
What SPL severity band is on file for Aspirin + Colestipol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Aspirin has 47 labeled pairs on file vs Colestipol's 24. In the minor band specifically: Aspirin has 32 (also Carisoprodol, Celecoxib, Diflunisal, Edoxaban); Colestipol has 23 (also Furosemide, Propranolol, Warfarin, Clindamycin).
What mechanism field is on file for Aspirin and Colestipol?
Colestipol does not seem to lower the levels of aspirin in your blood or stop it from being absorbed.
Aspirin carries more major-labeled pairs than Colestipol
SPL source-record counts only. This page's band is minor · classes on file: Aspirin (Antiplatelet / NSAID); Colestipol (Bile Acid Sequestrant).
Aspirin has 3 major-labeled pairs vs Colestipol's 0. This page itself is in the minor band, not the major band.
3 major · 12 moderate · 32 minor · 47 total
- Other minor peers for Aspirin
- Carisoprodol
- Celecoxib
- Diflunisal
- Edoxaban
0 major · 1 moderate · 23 minor · 24 total
- Other minor peers for Colestipol
- Furosemide
- Propranolol
- Warfarin
- Clindamycin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.