Colestipol and Furosemide Interaction
Drug interaction information between Colestipol and Furosemide.
Colestipol and Furosemide have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Colestipol and Furosemide. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Colestipol can trap furosemide in the gut, which stops the medicine from getting into your blood.
FDA Label Information
The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide, and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride.
Colestipol Also Interacts With
- Olmesartan moderate
- Aspirin minor
- Propranolol minor
- Warfarin minor
- Clindamycin minor
Furosemide Also Interacts With
- Dutasteride major
- Dutasteride/Tamsulosin major
- Tamsulosin major
- Cyclosporine moderate
- Lithium moderate
Frequently Asked Questions
What SPL severity band is on file for Colestipol + Furosemide?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Furosemide has 36 labeled pairs on file vs Colestipol's 24. In the minor band specifically: Colestipol has 23 (also Aspirin, Propranolol, Warfarin, Clindamycin); Furosemide has 29 (also Methotrexate, Norepinephrine, Ethacrynic Acid, Indomethacin).
What mechanism field is on file for Colestipol and Furosemide?
Colestipol can trap furosemide in the gut, which stops the medicine from getting into your blood.
Furosemide carries more major-labeled pairs than Colestipol
SPL source-record counts only. This page's band is minor · classes on file: Colestipol (Bile Acid Sequestrant); Furosemide (Loop Diuretic).
Furosemide has 3 major-labeled pairs vs Colestipol's 0. This page itself is in the minor band, not the major band.
0 major · 1 moderate · 23 minor · 24 total
- Other minor peers for Colestipol
- Aspirin
- Propranolol
- Warfarin
- Clindamycin
3 major · 4 moderate · 29 minor · 36 total
- Other minor peers for Furosemide
- Methotrexate
- Norepinephrine
- Ethacrynic Acid
- Indomethacin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.