What the FDA labels say about taking them together
Colestipol and furosemide
Colestipol's FDA label of February 19, 2024 names furosemide in its drug interactions section; the furosemide labels PlainMeds reads (4) do not name colestipol. The colestipol label: “The absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; …”
Check it at the source: the colestipol FDA label on DailyMed (effective February 19, 2024, Zydus Pharmaceuticals USA Inc.); the furosemide FDA label on DailyMed (effective September 30, 2025, Validus Pharmaceuticals LLC).
What does the colestipol label say about furosemide?
Colestipol label, drug interactionsThe absorption of tetracycline, furosemide, penicillin G, hydrochlorothiazide and gemfibrozil was significantly decreased when given simultaneously with colestipol hydrochloride; these drugs were not tested to determine the effect of administration one hour before colestipol hydrochloride.
Source: FDA drug label (Colestipol hydrochloride), Zydus Pharmaceuticals USA Inc., effective February 19, 2024 (SPL set 71f12e0d-373a-4867-b37c-f24d99c5ce95), via openFDA; the full label on DailyMed
What does the furosemide label say about colestipol?
Furosemide's label (effective September 30, 2025) and its 3 other brand-application labels do not name colestipol in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Lasix), Validus Pharmaceuticals LLC, effective September 30, 2025 (SPL set 2c9b4d8f-0770-482d-a9e6-9c616a440b1a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Colestipol | Furosemide | |
|---|---|---|
| Labeled for | High cholesterol | Heart failure, High blood pressure, Edema (fluid retention) |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.658 per tablet 1 g tablet | $0.490 per mL 20 mg/2 mL vial |
| Shortage now | No current entry | In shortage |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once