Colestipol and Warfarin Interaction
Drug interaction information between Colestipol and Warfarin.
Colestipol and Warfarin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Colestipol and Warfarin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Colestipol does not seem to lower the levels of warfarin in your blood or stop it from being absorbed.
FDA Label Information
No depressant effect on blood levels in humans was noted when colestipol hydrochloride was administered with any of the following drugs: aspirin, clindamycin, clofibrate, methyldopa, nicotinic acid (niacin), tolbutamide, phenytoin or warfarin.
Colestipol Also Interacts With
- Olmesartan moderate
- Furosemide minor
- Aspirin minor
- Propranolol minor
- Clindamycin minor
Warfarin Also Interacts With
- Fluoxetine major
- Tamoxifen major
- Ibuprofen moderate
- Aspirin moderate
- Diclofenac moderate
Frequently Asked Questions
What SPL severity band is on file for Colestipol + Warfarin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Warfarin has 163 labeled pairs on file vs Colestipol's 24. In the minor band specifically: Colestipol has 23 (also Furosemide, Aspirin, Propranolol, Clindamycin); Warfarin has 133 (also Atorvastatin, Amlodipine, Omeprazole, Famotidine).
What mechanism field is on file for Colestipol and Warfarin?
Colestipol does not seem to lower the levels of warfarin in your blood or stop it from being absorbed.
Warfarin carries more major-labeled pairs than Colestipol
SPL source-record counts only. This page's band is minor · classes on file: Colestipol (Bile Acid Sequestrant); Warfarin (Vitamin K Antagonist (Anticoagulant)).
Warfarin has 2 major-labeled pairs vs Colestipol's 0. This page itself is in the minor band, not the major band.
0 major · 1 moderate · 23 minor · 24 total
- Other minor peers for Colestipol
- Furosemide
- Aspirin
- Propranolol
- Clindamycin
2 major · 28 moderate · 133 minor · 163 total
- Other minor peers for Warfarin
- Atorvastatin
- Amlodipine
- Omeprazole
- Famotidine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.