Colestipol and Clindamycin Interaction
Drug interaction information between Colestipol and Clindamycin.
Colestipol and Clindamycin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Colestipol and Clindamycin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Colestipol does not seem to lower the levels of clindamycin in your blood or stop it from being absorbed.
FDA Label Information
No depressant effect on blood levels in humans was noted when colestipol hydrochloride was administered with any of the following drugs: aspirin, clindamycin, clofibrate, methyldopa, nicotinic acid (niacin), tolbutamide, phenytoin or warfarin.
Colestipol Also Interacts With
- Olmesartan moderate
- Furosemide minor
- Aspirin minor
- Propranolol minor
- Warfarin minor
Frequently Asked Questions
What SPL severity band is on file for Colestipol + Clindamycin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Colestipol has 24 labeled pairs on file vs Clindamycin's 2. In the minor band specifically: Colestipol has 23 (also Furosemide, Aspirin, Propranolol, Warfarin); Clindamycin has 2 (also Clindamycin Topical).
What mechanism field is on file for Colestipol and Clindamycin?
Colestipol does not seem to lower the levels of clindamycin in your blood or stop it from being absorbed.
Colestipol's labeled portfolio outnumbers Clindamycin
SPL source-record counts only. This page's band is minor · classes on file: Colestipol (Bile Acid Sequestrant); Clindamycin (Lincosamide Antibiotic).
0 major · 1 moderate · 23 minor · 24 total
- Other minor peers for Colestipol
- Furosemide
- Aspirin
- Propranolol
- Warfarin
0 major · 0 moderate · 2 minor · 2 total
- Other minor peers for Clindamycin
- Clindamycin Topical
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.