Aspirin and Carisoprodol Interaction
Drug interaction information between Aspirin and Carisoprodol.
Aspirin and Carisoprodol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Aspirin and Carisoprodol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Aspirin makes your liver work faster to break down carisoprodol. This can cause the carisoprodol to leave your body too quickly and not work as well.
FDA Label Information
Low dose aspirin also showed an induction effect on CYP2C19.
Aspirin Also Interacts With
- Atenolol major
- Fluoxetine major
- Ibandronate major
- Alendronate moderate
- Apixaban moderate
Carisoprodol Also Interacts With
- Omeprazole minor
- Rifampin minor
- Fluvoxamine minor
Frequently Asked Questions
What SPL severity band is on file for Aspirin + Carisoprodol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Aspirin has 47 labeled pairs on file vs Carisoprodol's 4. In the minor band specifically: Aspirin has 32 (also Celecoxib, Colestipol, Diflunisal, Edoxaban); Carisoprodol has 4 (also Omeprazole, Rifampin, Fluvoxamine).
What mechanism field is on file for Aspirin and Carisoprodol?
Aspirin makes your liver work faster to break down carisoprodol. This can cause the carisoprodol to leave your body too quickly and not work as well.
Aspirin carries more major-labeled pairs than Carisoprodol
SPL source-record counts only. This page's band is minor · classes on file: Aspirin (Antiplatelet / NSAID); Carisoprodol (Centrally Acting Muscle Relaxant).
Aspirin has 3 major-labeled pairs vs Carisoprodol's 0. This page itself is in the minor band, not the major band.
3 major · 12 moderate · 32 minor · 47 total
- Other minor peers for Aspirin
- Celecoxib
- Colestipol
- Diflunisal
- Edoxaban
0 major · 0 moderate · 4 minor · 4 total
- Other minor peers for Carisoprodol
- Omeprazole
- Rifampin
- Fluvoxamine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.