HIGH-VOLUME · HOSP-HEAVY
doxycycline Side Effects
doxycycline (also sold as Vibramycin, Doryx) is HIGH-VOLUME in this FAERS book #112 of 524 by FAERS report count. Signature opener: HOSP-HEAVY - 32.1% mention hospitalization (20,682 reports).
Data updated 2026-05-15
- 64,488
- FAERS reports
FAERS voluntary reports, 2003 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
doxycycline: 32.1% mention hospitalization (20,682 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #112 of 524 by FAERS report count.
High-report extract for doxycycline (Vibramycin): 64,488 FAERS rows (2003-2025). Top named reactions: NAUSEA, FATIGUE, RASH. Outcome stamps DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (2003–2025). Stamps CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
NAUSEA leads 4,769 of 64,488 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (14,486 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (6,297 reports, 9.8%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 1,421 |
| FATIGUE | 1,050 |
| HYPERTENSION | 961 |
| HYPOAESTHESIA | 956 |
| GENERAL PHYSICAL HEALTH DETERIORATION | 945 |
| VOMITING | 941 |
| HYPERSENSITIVITY | 922 |
| RASH | 921 |
| GLOSSODYNIA | 916 |
| PYREXIA | 916 |
| IMPAIRED HEALING | 911 |
| TYPE 2 DIABETES MELLITUS | 906 |
| HELICOBACTER INFECTION | 905 |
| INJURY | 905 |
| HAND DEFORMITY | 901 |
| INFECTION | 899 |
| FIBROMYALGIA | 879 |
| HEPATIC ENZYME INCREASED | 874 |
| JOINT SWELLING | 871 |
Reactions in Hospitalization Reports
Hospitalization is HEAVY (20,682, 32.1% of the book). Top reactions in those rows:
| Reaction | Reports |
|---|---|
| DYSPNOEA | 2,219 |
| FATIGUE | 2,072 |
| NAUSEA | 1,910 |
| VOMITING | 1,867 |
| PAIN | 1,856 |
| PNEUMONIA | 1,843 |
| DIARRHOEA | 1,835 |
| PYREXIA | 1,750 |
| RASH | 1,689 |
| HEADACHE | 1,561 |
| MALAISE | 1,470 |
| CONDITION AGGRAVATED | 1,419 |
| HYPERTENSION | 1,373 |
| ARTHRALGIA | 1,371 |
| INFECTION | 1,333 |
| ASTHENIA | 1,305 |
| ANXIETY | 1,281 |
| DIZZINESS | 1,266 |
How to read doxycycline FAERS figures (CASELOAD · DEATH-HEAVY · HOSP-HEAVY)
FAERS holds 64,488 voluntary reports linked to doxycycline (Vibramycin, Doryx), 2003-2025. Death is listed on 6,297 (9.8%). Hospitalization appears on 20,682 (32.1%). Top co-reported indication: Product Used For Unknown Indication.
CASELOAD books overweight common drugs and loud reporting cultures; HOSP-HEAVY is the page opener, not a per-patient risk.
Read with doxycycline
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.
ABS(total_reports) peer at 64,404 FAERS cases (Δ 84 lighter vs doxycycline); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 64,119 FAERS cases (Δ 369 lighter vs doxycycline); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 65,067 FAERS cases (Δ 579 heavier vs doxycycline); DEATH-HEAVY · HOSP-HEAVY · FEMALE-LED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(total_reports) peer at 63,762 FAERS cases (Δ 726 lighter vs doxycycline); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 52.3 pp vs doxycycline's DEATH-HEAVY): CASELOAD · HOSP-MID.
doxycycline stamps DEATH-HEAVY · HOSP-HEAVY; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload CASELOAD and the label guide.