Zolpidem and Haloperidol Interaction
Drug interaction information between Zolpidem and Haloperidol.
Zolpidem and Haloperidol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Zolpidem and Haloperidol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Haloperidol does not have any measurable effect on how zolpidem works or moves through the body.
FDA Label Information
Haloperidol A study involving haloperidol and Zolpidem revealed no effect of haloperidol on the pharmacokinetics or pharmacodynamics of Zolpidem.
Zolpidem Also Interacts With
- Ketoconazole moderate
- Rifampin moderate
- Imipramine moderate
- Chlorpromazine moderate
- Sertraline minor
Haloperidol Also Interacts With
- Fluoxetine moderate
- Tetrabenazine moderate
- Bromocriptine minor
- Bupropion minor
- Carbamazepine minor
Frequently Asked Questions
What SPL severity band is on file for Zolpidem + Haloperidol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Haloperidol has 14 labeled pairs on file vs Zolpidem's 9. In the minor band specifically: Zolpidem has 5 (also Sertraline, Fluoxetine, Darunavir, Nirmatrelvir/Ritonavir); Haloperidol has 12 (also Bromocriptine, Bupropion, Carbamazepine, Clomipramine).
What mechanism field is on file for Zolpidem and Haloperidol?
Haloperidol does not have any measurable effect on how zolpidem works or moves through the body.
Haloperidol's labeled portfolio outnumbers Zolpidem
SPL source-record counts only. This page's band is minor · classes on file: Zolpidem (Non-Benzodiazepine Hypnotic (Z-Drug)); Haloperidol (Typical Antipsychotic).
0 major · 4 moderate · 5 minor · 9 total
- Other minor peers for Zolpidem
- Sertraline
- Fluoxetine
- Darunavir
- Nirmatrelvir/Ritonavir
0 major · 2 moderate · 12 minor · 14 total
- Other minor peers for Haloperidol
- Bromocriptine
- Bupropion
- Carbamazepine
- Clomipramine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.